Area of research
Cell Biology · Epidemiology
Research interest
Research focused on Prostate cancer and ATF4, with related work in mTORC1, Circadian clock, Unfolded protein response. Notable publications include 'ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth', 'ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression', and 'Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR'.
Radiotherapy toxicities: mechanisms, management, and future directions
The radiogenomic and spatiogenomic landscapes of glioblastoma and their relationship to oncogenic drivers
Enhancing outcomes in medically inoperable early-stage NSCLC with gut-targeted antibiotics and stereotactic body radiotherapy: results from a randomized pilot study
Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression
Roadmap for precision preclinical x-ray radiation studies
Shining a FLASHlight on Ultrahigh Dose-Rate Radiation and Possible Late Toxicity
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
Development of a stress response therapy targeting aggressive prostate cancer
A PERK–miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival
Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism
ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth
miR-211 Is a Prosurvival MicroRNA that Regulates chop Expression in a PERK-Dependent Manner