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Ethan Bier

University of California San Diego · US
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Area of research
Molecular Biology · Insect Science
Research interest
Research interests include CRISPR and Genetic Engineering, Developmental Biology and Gene Regulation, Insect Resistance and Genetics, and Insect symbiosis and bacterial influences.
h-index
59
citations
13,508
works
152
NIH funding
primary concept
email

Recent publications

Driving a protective allele of the mosquito FREP1 gene to combat malaria
Nature 2025cited by 9position: lastdoi
Conceptual risk assessment of mosquito population modification gene-drive systems to control malaria transmission: preliminary hazards list workshops
Frontiers in Bioengineering and Biotechnology 2023cited by 9position: middledoi
Gene drives gaining speed
Nature Reviews Genetics 2021cited by 238position: firstdoi
Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly
BMC Biology 2021cited by 123position: middledoi
Inherently confinable split-drive systems in Drosophila
Nature Communications 2021cited by 94position: lastdoi
Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline
PLoS Biology 2021cited by 48position: middledoi
Efficient population modification gene-drive rescue system in the malaria mosquito Anopheles stephensi
Nature Communications 2020cited by 202position: middledoi
A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
Nature Communications 2020cited by 92position: middledoi
Active Genetic Neutralizing Elements for Halting or Deleting Gene Drives
Molecular Cell 2020cited by 73position: lastdoi
Super-Mendelian inheritance mediated by CRISPR–Cas9 in the female mouse germline
Nature 2019cited by 284position: middledoi
Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes
G3 Genes Genomes Genetics 2019cited by 92position: middledoi
Efficient allelic-drive in Drosophila
Nature Communications 2019cited by 82position: lastdoi
Advances in Engineering the Fly Genome with the CRISPR-Cas System
Genetics 2018cited by 179position: firstdoi
Rules of the road for insect gene drive research and testing
Nature Biotechnology 2017cited by 100position: middledoi
Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito <i>Anopheles stephensi</i>
Proceedings of the National Academy of Sciences 2015cited by 1,019position: middledoi
The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations
Science 2015cited by 634position: lastdoi
BMP gradients: A paradigm for morphogen-mediated developmental patterning
Science 2015cited by 315position: firstdoi
Safeguarding gene drive experiments in the laboratory
Science 2015cited by 287position: middledoi
The dawn of active genetics
BioEssays 2015cited by 124position: lastdoi
RAB11-mediated trafficking in host–pathogen interactions
Nature Reviews Microbiology 2014cited by 94position: lastdoi
Cholera Toxin Disrupts Barrier Function by Inhibiting Exocyst-Mediated Trafficking of Host Proteins to Intestinal Cell Junctions
Cell Host & Microbe 2013cited by 104position: lastdoi
Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3
Cell Metabolism 2012cited by 290position: middledoi

Grants

Multiplex analysis of boundary formation in the Drosophila embryo
NSF0920785$250,0002009–2011PIRePORTER
Analysis of Wing Vein Specification in Drosophila
NSF0744662$406,0002008–2011PIRePORTER
Multiplex in Situ Visualization of the Drosophila Transcriptome in Blastoderm Embryos
NSF0120728$1,350,0002001–2007PIRePORTER
Analysis of the Drosophila Gene Rhomboid
NSF0094634$420,0002001–2004PIRePORTER
Analysis of the Drosophila Gene Rhomboid
NSF9604048$409,0011997–2000PIRePORTER
Analysis of the Drosophila Gene Rhomboid
NSF9318242$330,0001994–1997PIRePORTER

Frequent collaborators

Valentino M. Gantz · University of San Diego10 papers (2015–2021)John M. Marshall · Innovative Genomics Institute6 papers (2020–2025)Anthony A. James · University of California, Irvine4 papers (2015–2023)Jared B. Bennett · University of California, Berkeley4 papers (2020–2021)Xiangru Xu · China Agricultural University3 papers (2019–2020)Omar S. Akbari · University of Southern California3 papers (2019–2021)Annabel Guichard · University of California San Diego3 papers (2013–2019)Anna Buchman · University of California San Diego3 papers (2019–2021)Emily A. Bulger · Gladstone Institutes2 papers (2020–2020)Hannah A. Grunwald · University of California San Diego2 papers (2019–2021)J. J. Emerson · University of California, Berkeley2 papers (2020–2021)Arunachalam Ramaiah · Georgia Department of Public Health2 papers (2020–2021)Adriana Adolfi · Liverpool School of Tropical Medicine2 papers (2020–2021)Carissa F. Klanseck · University of California San Diego2 papers (2019–2020) · 2 papers (2015–2020)Victor Nizet · CNR de la Résistance aux Antibiotiques2 papers (2013–2014)Bhagyashree Kaduskar · Tata Institute for Genetics and Society2 papers (2019–2021)Gerard Terradas · Center for Disease Dynamics, Economics & Policy2 papers (2020–2021)George Dimopoulos · Johns Hopkins University2 papers (2023–2025)Kimberly L. Cooper · Columbia University Irving Medical Center2 papers (2019–2021)
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