Area of research
Molecular Medicine · Molecular Biology
Research interest
Research focused on Autophagy and Diosgenin, with related work in In vivo, PI3K/AKT/mTOR pathway, ATG5. Notable publications include 'Doxorubicin-loaded bacterial outer-membrane vesicles exert enhanced anti-tumor efficacy in non-small-cell lung cancer', 'A biomimetic nanovector-mediated targeted cholesterol-conjugated siRNA delivery for tumor gene therapy', and 'Diosgenin promotes antitumor immunity and PD-1 antibody efficacy against melanoma by regulating intestinal microbiota'.
A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing
Transcriptomic investigations of polymyxins and colistin/sulbactam combination against carbapenem-resistant <i>Acinetobacter baumannii</i>
Novel nitroxoline derivative combating resistant bacterial infections through outer membrane disruption and competitive NDM-1 inhibition
Engineering Methyltransferase and Sulfoxide Synthase for High-Yield Production of Ergothioneine
Pharmacokinetics and pharmacodynamics of peptide antibiotics
Doxorubicin-loaded bacterial outer-membrane vesicles exert enhanced anti-tumor efficacy in non-small-cell lung cancer
Diosgenin promotes antitumor immunity and PD-1 antibody efficacy against melanoma by regulating intestinal microbiota
Blocking autophagy improves the anti-tumor activity of afatinib in lung adenocarcinoma with activating EGFR mutations in vitro and in vivo
Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells
C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells
Baicalin inhibits autophagy induced by influenza A virus H3N2
Autophagy Plays a Critical Role in ChLym-1-Induced Cytotoxicity of Non-Hodgkin’s Lymphoma Cells
A biomimetic nanovector-mediated targeted cholesterol-conjugated siRNA delivery for tumor gene therapy