Area of research
Pharmacology · Oncology
Research interest
Research focused on Cell biology and Physiologically based pharmacokinetic modelling, with related work in Biopharmaceutics, Bioavailability, CpG Oligodeoxynucleotide. Notable publications include 'IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results', 'The epidermal growth factor receptor regulates cofilin activity and promotes transmissible gastroenteritis virus entry into intestinal epithelial cells', and 'From nasal to basal: single-cell sequencing of the bursa of Fabricius highlights the IBDV infection mechanism in chickens'.
Trained immunity using probiotics and inactivated pathogens enhances resistance to Salmonella enterica serovar Typhimurium infection by activating the cGAS-STING signal pathway in mice and chickens
A double-edged sword in antiviral defence: ATG7 binding dicer to promote virus replication
Surfactin from <i>Bacillus subtilis</i> enhances immune response and contributes to the maintenance of intestinal microbial homeostasis
IBV QX affects the antigen presentation function of BMDCs through nonstructural protein16
Immune Responses Induced by Recombinant Bacillus subtilis Expressing the PEDV Spike Protein Targeted at Microfold Cells
From nasal to basal: single-cell sequencing of the bursa of Fabricius highlights the IBDV infection mechanism in chickens
The mechanism of antigen-presentation of avian bone marrowed dendritic cells suppressed by infectious bronchitis virus
Bacillus subtilis Spore-Trained Dendritic Cells Enhance the Generation of Memory T Cells via ICAM1
miR29a and miR378b Influence CpG-Stimulated Dendritic Cells and Regulate cGAS/STING Pathway
Mucosal and systemic immune responses induced by intranasal immunization of recombinant <i>Bacillus subtilis</i> expressing the P97R1, P46 antigens of <i>Mycoplasma hyopneumoniae</i>
Intranasal administration with recombinant Bacillus subtilis induces strong mucosal immune responses against pseudorabies
Microarray analysis of infectious bronchitis virus infection of chicken primary dendritic cells
Genome-wide profiling of microRNAs reveals novel insights into the interactions between H9N2 avian influenza virus and avian dendritic cells
Oscheius microvilli n. sp. (Nematoda: Rhabditidae): A Facultatively Pathogenic Nematode from Chongming Island, China
H9N2 Avian Influenza Virus Protein PB1 Enhances the Immune Responses of Bone Marrow-Derived Dendritic Cells by Down-Regulating miR375
H9N2 avian influenza virus enhances the immune responses of BMDCs by down-regulating miR29c
IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results
The epidermal growth factor receptor regulates cofilin activity and promotes transmissible gastroenteritis virus entry into intestinal epithelial cells
IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes
Immune responses induced by recombinant Bacillus subtilis expressing the spike protein of transmissible gastroenteritis virus in pigs
Genome-wide profiling of chicken dendritic cell response to infectious bursal disease
Modulation of Mammary Gland Development and Milk Production by Growth Hormone Expression in GH Transgenic Goats
Bacillus amyloliquefaciens SQR9 induces dendritic cell maturation and enhances the immune response against inactivated avian influenza virus
MiR674 inhibits the neuraminidase-stimulated immune response on dendritic cells via down-regulated Mbnl3
CpG Oligodeoxynucleotides Facilitate Delivery of Whole Inactivated H9N2 Influenza Virus via Transepithelial Dendrites of Dendritic Cells in Nasal Mucosa
Transcriptome analysis of the mammary gland from GH transgenic goats during involution
Whole inactivated avian Influenza H9N2 viruses induce nasal submucosal dendritic cells to sample luminal viruses via transepithelial dendrites and trigger subsequent DC maturation
CpG DNA assists the whole inactivated H9N2 influenza virus in crossing the intestinal epithelial barriers via transepithelial uptake of dendritic cell dendrites
Effects of virulent and attenuated transmissible gastroenteritis virus on the ability of porcine dendritic cells to sample and present antigen
The stimulatory effect of different CpG oligonucleotides on the maturation of chicken bone marrow-derived dendritic cells