Area of research
Immunology · Epidemiology
Research interest
Research interests include Immunodeficiency and Autoimmune Disorders, Mycobacterium research and diagnosis, Tuberculosis Research and Epidemiology, and Immune Cell Function and Interaction.
Monoallelic expression can govern penetrance of inborn errors of immunity
Mycobacterium tuberculosis resisters despite HIV exhibit activated T cells and macrophages in their pulmonary alveoli
Human LY9 governs CD4 <sup>+</sup> T cell IFN-γ immunity to <i>Mycobacterium tuberculosis</i>
A human YEATS4 variant confers resistance to TST and IGRA conversion despite Mycobacterium tuberculosis exposure
FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
Tuberculosis in otherwise healthy adults with inherited TNF deficiency
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling
Helper T cell immunity in humans with inherited CD4 deficiency
Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals
Human inherited PD-L1 deficiency is clinically and immunologically less severe than PD-1 deficiency.
Recombinant IFN-γ1b Treatment in a Patient with Inherited IFN-γ Deficiency
IL-7–dependent and –independent lineages of IL-7R–dependent human T cells
Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe
Human IL-23 is essential for IFN-γ–dependent immunity to mycobacteria
Human inherited CCR2 deficiency underlies progressive polycystic lung disease
Human inherited complete STAT2 deficiency underlies inflammatory viral diseases
Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria
Anti-GM-CSF Neutralizing Autoantibodies in Colombian Patients with Disseminated Cryptococcosis
Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity
Mendelian Susceptibility to Mycobacterial Disease (MSMD): Clinical, Immunological, and Genetic Features of 22 Patients from 15 Moroccan Kindreds
Inborn Errors of Immunity—the Sri Lankan Experience 2010–2022
Human IL-23 is essential for IFN-γ-dependent immunity to mycobacteria
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
Human T-bet governs the generation of a distinct subset of CD11c <sup>high</sup> CD21 <sup>low</sup> B cells
Impaired IL-23–dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency
Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis
Partial human Janus kinase 1 deficiency predominantly impairs responses to interferon gamma and intracellular control of mycobacteria
Mendelian Susceptibility to Mycobacterial Disease: Retrospective Clinical and Genetic Study in Mexico