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Xuhui Huang

University of Wisconsin–Madison · US
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Area of research
Molecular Biology · Atomic and Molecular Physics, and Optics
Research interest
Research interests include Protein Structure and Dynamics, RNA and protein synthesis mechanisms, DNA and Nucleic Acid Chemistry, and Spectroscopy and Quantum Chemical Studies.
h-index
63
citations
13,528
works
314
NIH funding
primary concept
email

Recent publications

Smart Nanoarchitectures for Precision RNA Delivery: Harnessing Endogenous and Exogenous Stimuli in Cancer Treatment
Theranostics 2025cited by 17position: middledoi
Molecular basis for noncanonical transcription initiation from Np4A alarmones
Nature Chemical Biology 2025cited by 2position: middledoi
Design, synthesis, and biological evaluation of Osimertinib–Cy7 (OSA-Cy7) conjugate as potential theranostic agent targeting activating EGFR mutations
BMC Biotechnology 2025cited by 1position: middledoi
B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan’s syndrome mutations
Proceedings of the National Academy of Sciences 2023cited by 10position: middledoi
circular RNA CircITCH (has-circ-0001141) suppresses hepatocellular carcinoma (HCC) progression by sponging miR-184
Research Square 2021cited by 2position: middledoi
Non-aromatic annulene-based aggregation-induced emission system via aromaticity reversal process
Nature Communications 2019cited by 185position: middledoi
Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs
Cell Reports 2017cited by 69position: middledoi
AIEgen-based theranostic system: targeted imaging of cancer cells and adjuvant amplification of antitumor efficacy of paclitaxel
Chemical Science 2016cited by 108position: middledoi
Elucidation of the Dynamics of Transcription Elongation by RNA Polymerase II using Kinetic Network Models
Accounts of Chemical Research 2016cited by 66position: lastdoi
Conformational Dynamics of apo‐GlnBP Revealed by Experimental and Computational Analysis
Angewandte Chemie International Edition 2016cited by 50position: middledoi
Millisecond dynamics of RNA polymerase II translocation at atomic resolution
Proceedings of the National Academy of Sciences 2014cited by 155position: lastdoi
Constructing kinetic models to elucidate structural dynamics of a complete RNA polymerase II elongation cycle
Physical Biology 2014cited by 16position: lastdoi

Grants

Collaborative Research: Developing a Polarizable 3DRISM Implicit Solvent Model for AMOEBA Solutes to Enable Efficient and Accurate RNA Simulations
NSF2510097$378,0252025–2028PIRePORTER

Frequent collaborators

Ben Zhong Tang · Chinese University of Hong Kong2 papers (2016–2019)Lu Zhang · New York University2 papers (2016–2016)Dong Wang · University of Montana2 papers (2014–2016) · 2 papers (2016–2025)Xiaoyan Zheng · Jiangsu University2 papers (2016–2019)Lin‐Tai Da · Florida State University2 papers (2014–2014)Xiao Ke · Guangzhou University of Chinese Medicine1 papers (2017–2017)Yuan Shang · Glaxosmithkline (Finland)1 papers (2017–2017)Wei He · Soochow University1 papers (2019–2019)Mengjie Liu · Fudan University1 papers (2025–2025) · 1 papers (2016–2016)Zhen Xu · University of Iowa1 papers (2023–2023)Hao Li · Agency for Science, Technology and Research1 papers (2017–2017)Mingjie Zhang · National University of Defense Technology1 papers (2017–2017)Bing Wang · New York University1 papers (2025–2025)Yue Li · Hebei Medical University1 papers (2025–2025)Bin Liu · Beijing Institute of Technology1 papers (2016–2016)Chao Chen · The First Affiliated Hospital, Sun Yat-sen University1 papers (2016–2016)Jianwei Liu · Xuzhou Medical College1 papers (2016–2016)Zhijun Liu · Georgia Institute of Technology1 papers (2016–2016)
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