Area of research
Molecular Biology · Biophysics
Research interest
Our research is organised into six primary Scientific Programmes, each defining a major area of research with a particular biological, disease, analytic or generative focus. In addition, our Associate Research programmes pioneer new approaches to studying health and disease.
Mapping cells through time and space with moscot
Towards multimodal foundation models in molecular cell biology
Transformers and genome language models
A foundation model to predict and capture human cognition
Quantitative characterization of cell niches in spatially resolved omics data
Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes
Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression
OmniPath: integrated knowledgebase for multi-omics analysis
Single-cell multiome and spatial profiling reveals pancreas cell type–specific gene regulatory programs of type 1 diabetes progression
2D, or not 2D? Investigating Vertical Signal Integrity of Tissue Slices
Pertpy: an end-to-end framework for perturbation analysis
How to build the virtual cell with artificial intelligence: Priorities and opportunities
CellRank 2: unified fate mapping in multiview single-cell data
SpatialData: an open and universal data framework for spatial omics
An integrated transcriptomic cell atlas of human neural organoids
Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts
The future of rapid and automated single-cell data analysis using reference mapping
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection
Considerations for building and using integrated single-cell atlases
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery
Mapping lineage-traced cells across time points with moslin
Centaur: a foundation model of human cognition
Polyploidisation pleiotropically buffers ageing in hepatocytes
RegVelo: Gene-regulatory-informed dynamics of single cells
ProCyon: A multimodal foundation model for protein phenotypes
HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma
Best practices for single-cell analysis across modalities
An integrated cell atlas of the lung in health and disease
The scverse project provides a computational ecosystem for single-cell omics data analysis