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Zhigang Tian

Hua Medicine (China) · CN
Area of research
Immunology · Oncology
Research interest
Research interests include Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immune cells in cancer, and Immunotherapy and Immune Responses.
h-index
95
citations
38,048
works
684
NIH funding
primary concept
Medicine
email

Recent publications

RSAD2: A pathogenic interferon-stimulated gene at the maternal-fetal interface of patients with systemic lupus erythematosus
Cell Reports Medicine 2025cited by 16position: middledoi
αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models
Nature Communications 2025cited by 4position: middledoi
Targeting myeloid-derived suppressor cells promotes antiparasitic T-cell immunity and enhances the efficacy of PD-1 blockade
Nature Communications 2024cited by 18position: middledoi
Author Correction: Targeting myeloid-derived suppressor cells promotes antiparasitic T-cell immunity and enhances the efficacy of PD-1 blockade
Nature Communications 2024cited by 2position: middledoi
Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine
Cell 2023cited by 77position: middledoi
Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome
Cell 2021cited by 215position: middledoi
METTL3-mediated m6A RNA methylation promotes the anti-tumour immunity of natural killer cells
Nature Communications 2021cited by 190position: lastdoi
γδT Cells Suppress Liver Fibrosis via Strong Cytolysis and Enhanced NK Cell-Mediated Cytotoxicity Against Hepatic Stellate Cells
Frontiers in Immunology 2019cited by 65position: middledoi
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion
Nature Communications 2018cited by 101position: lastdoi
Chimeric antigen receptor (CAR)-transduced natural killer cells in tumor immunotherapy
Acta Pharmacologica Sinica 2017cited by 164position: middledoi
NK cell subsets in autoimmune diseases
Journal of Autoimmunity 2017cited by 65position: lastdoi
Contribution of inhibitory receptor TIGIT to NK cell education
Journal of Autoimmunity 2017cited by 52position: lastdoi
Deficiency of the AIM2–ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection
The Journal of Immunology 2017cited by 49position: middledoi
HBV inhibits LPS-induced NLRP3 inflammasome activation and IL-1β production via suppressing the NF-κB pathway and ROS production
Journal of Hepatology 2016cited by 354position: lastdoi
High NKG2A expression contributes to NK cell exhaustion and predicts a poor prognosis of patients with liver cancer
OncoImmunology 2016cited by 277position: lastdoi
Exosomes mediate hepatitis B virus (HBV) transmission and NK-cell dysfunction
Cellular and Molecular Immunology 2016cited by 217position: middledoi
Differential phenotypic and functional properties of liver-resident NK cells and mucosal ILC1s
Journal of Autoimmunity 2015cited by 96position: lastdoi
Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells
eLife 2014cited by 546position: middledoi
NK cell receptor imbalance and NK cell dysfunction in HBV infection and hepatocellular carcinoma
Cellular and Molecular Immunology 2014cited by 200position: lastdoi
Histone deacetylase inhibitor SAHA epigenetically regulates miR-17-92 cluster and MCM7 to upregulate MICA expression in hepatoma
British Journal of Cancer 2014cited by 115position: middledoi
Tissue-resident natural killer cells and their potential diversity
Seminars in Immunology 2014cited by 104position: middledoi
Liver-resident NK cells confer adaptive immunity in skin-contact inflammation
Journal of Clinical Investigation 2013cited by 529position: lastdoi
Natural killer cells promote immune tolerance by regulating inflammatory T <sub>H</sub> 17 cells at the human maternal–fetal interface
Proceedings of the National Academy of Sciences 2012cited by 291position: middledoi
Regulatory NK cells in autoimmune disease
Journal of Autoimmunity 2012cited by 113position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Cai Zhang · Shandong University8 papers (2012–2019)Haiming Wei · Fudan University8 papers (2012–2025)Rui Sun · The Affiliated Yongchuan Hospital of Chongqing Medical University8 papers (2012–2025)Haoyu Sun · Fudan University5 papers (2014–2025)Wayne M. Yokoyama · Center for Rheumatology5 papers (2013–2017)Hui Peng · Institute of Biomedical Science5 papers (2013–2025)Dorothy K. Sojka · Loyola University Chicago3 papers (2013–2014)Cheng Sun · Anhui Medical University3 papers (2014–2018)Jian Zhang · Fudan University3 papers (2016–2018)Hao Wen · Xinjiang Medical University3 papers (2016–2024)Jiaxi Song · Nanjing University of Chinese Medicine3 papers (2016–2021)Peixiang Lan · Ministry of Education of the People's Republic of China3 papers (2014–2018)Shu Zhu · University of Science and Technology of China3 papers (2021–2023)Richard A. Flavell · University of California, San Francisco3 papers (2021–2023)Qiuju Han · Shandong University3 papers (2016–2018)Chuanshan Zhang · Xinjiang University3 papers (2016–2024)Meijuan Zheng · Nantong University2 papers (2016–2021)Adilai duolikun · Xinjiang Medical University2 papers (2024–2024)Jing Li · Guangzhou University of Chinese Medicine2 papers (2024–2024)Liang Li · Justus-Liebig-Universität Gießen2 papers (2024–2024)