Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Chemical Synthesis and Analysis, Gastric Cancer Management and Outcomes, Carbohydrate Chemistry and Synthesis, and Traditional and Medicinal Uses of Annonaceae.
Design and development of 1,5-diarylpyrazole-based multitarget-directed ligands as dual COX-2/HDAC6 inhibitors for Alzheimer's disease therapy: Molecular dynamics and experimental insights
Synthesis and Chemical Structure of the Cyclic Heptapeptide Stylissamide H.
Synthesis of Stylissamide B, a Pro-Rich Cyclic Heptapeptide Isolated From the Marine Sponge Stylissa caribica.
Design and Synthesis of Fluorescence-Labeled TAK779 Analogs as Chemical Probes.
Microwave‐Assisted Oxidation with Catalyzed by
<i>N</i>
‐Hydroxyphtalimide Derivatives
Antifungal activity of GH64 β-1,3-glucanase from the gram-negative bacterium Flavobacterium johnsoniae
Exploring the green synthesis of silver nanoparticles using natural extracts and their potential for cancer treatment.
Design of Multi-Target drugs of HDACs and other Anti-Alzheimer related Targets: Current strategies and future prospects in Alzheimer's diseases therapy.
HAMARI’S CONTRIBUTION TO THE ASYMMETRIC SYNTHESIS OF TAILOR-MADE AMINO ACIDS
HAMARI’S CONTRIBUTION TO THE ASYMMETRIC SYNTHESIS OF TAILOR-MADE AMINO ACIDS
Synthesis and Structural Revision of the Cyclic Hexapeptide Dimers Antatollamides A and B.
Synthesis and evaluation of catecholamine derivatives as amyloid-beta aggregation inhibitors.
Development of 1,5-diarylpyrazoles as EGFR/JNK-2 dual inhibitors: design, synthesis, moleecular docking, and bioactivity evaluation.
Redesign of a thioflavin-T-binding protein with a flat β-sheet to evaluate a thioflavin-T-derived photocatalyst with enhanced affinity.
SpyTag Peptide with Alkoxyl Aspartic Acids for pH-Dependent Activation of the SpyCatcher/Tag System.
Dynamic Thermodynamic Resolution of Unprotected Amino Acids Using Ni(II) Chiral Schiff Bases
Secretoglobin 3A2 peptides have therapeutic potential for allergic airway inflammation.
Determination of the amino linkage of the D-Dab residue of the cyclic lipo-octapeptide occidiofungins A-D and the antifungal activity of their analogues.
Addition of α-1,3-glucan-binding domains to α-1,3-glucanase Agn1p from Schizosaccharomyces pombe enhances hydrolytic activity of insoluble α-1,3-glucan.
Domain structure and function of α-1,3-glucanase Agl-EK14 from the gram-negative bacterium Flavobacterium sp. EK-14.
Nigero-oligosaccharide production by enzymatic hydrolysis from alkaline-pretreated α-1,3-glucan.
α-1,3-Glucanase from the gram-negative bacterium Flavobacterium sp. EK-14 hydrolyzes fungal cell wall α-1,3-glucan.
Development and Assessment of 1,5-Diarylpyrazole/Oxime Hybrids Targeting EGFR and JNK-2 as Antiproliferative Agents: A Comprehensive Study through Synthesis, Molecular Docking, and Evaluation.
Structure-Activity Relationship Study of <i>N</i>-Hydroxyphtalimide Derivatives for the Detection of Amines during Fmoc-Solid-Phase Peptide Synthesis.
Design of the peptide C-terminus protecting group and application for the peptide fragment coupling reaction
Synthesis and evaluation of l-dopa and L-Tyr derivatives as amyloid-beta aggregation inhibitors
Heterologous expression of α-1,3-glucanase Agn1p from Schizosaccharomyces pombe, and efficient production of nigero-oligosaccharides by enzymatic hydrolysis from solubilized α-1,3;1,6-glucan.
New pharmaceuticals approved by FDA in 2020: Small-molecule drugs derived from amino acids and related compounds.
Construction of a fusion protein consisting of α-1,3-glucan-binding domains and tetrameric red fluorescent protein, which is involved in the aggregation of α-1,3-glucan and inhibition of fungal biofilm formation.
Design, synthesis, and evaluation of the self-assembled antimicrobial peptides based on the ovalbumin-derived peptide TK913.