Area of research
Oncology · Cell Biology
Research interest
Research focused on Mesothelioma and Germline, with related work in Cancer research, BAP1, Mesothelial Cell. Notable publications include 'Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy', 'Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma', and 'BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos'.
Germline <i>BARD1</i> variants predispose to mesothelioma by impairing DNA repair and calcium signaling
HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma
BAP1 is a novel regulator of HIF-1α
BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos
Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy
Heterozygous germline <i>BLM</i> mutations increase susceptibility to asbestos and mesothelioma
CD44 Regulates Formation of Spheroids and Controls Organ-Specific Metastatic Colonization in Epithelial Ovarian Carcinoma