Area of research
Genetics · Immunology
Research interest
Research interests include Chronic Lymphocytic Leukemia Research, Immune Cell Function and Interaction, CAR-T cell therapy research, and Lymphoma Diagnosis and Treatment.
Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target
Longitudinal omics data and preclinical treatment suggest the proteasome inhibitor carfilzomib as therapy for ibrutinib-resistant CLL
198 | CD3xCD20 BISPECIFIC EPCORITAMAB INDUCES ANTITUMOR ACTIVITY AND FAVORABLE T‐CELL DYNAMICS OVER TIME WITH PROLONGED THERAPY
Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities
CD20-bispecific antibodies improve response to CD19-CAR T cells in lymphoma in vitro and CLL in vivo models
The diversity of the microbiome impacts chronic lymphocytic leukemia development in mice and humans
T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia
Lessons learned from the Eµ-TCL1 mouse model of CLL
Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression
Interleukin-27 potentiates CD8+ T-cell-mediated antitumor immunity in chronic lymphocytic leukemia
Simultaneous Inhibition of PI3Kgamma and PI3Kdelta Deteriorates T-cell Function With Implications for Chronic Lymphocytic Leukemia
scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved pooled single-cell RNA sequencing analysis
TIGIT: an immune checkpoint beyond T cells in chronic lymphocytic leukemia
Multi-layered chromatin proteomics identifies cell vulnerabilities in DNA repair
Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities
High-dimensional single-cell definition of CLL T cells identifies Galectin-9 as novel immunotherapy target
Single-Cell Omics Analyses Identify the TIM-3 Ligand Galectin-9 As Novel Immunotherapy Target for Chronic Lymphocytic Leukemia
Editorial: New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Tumor Immunology and Immunotherapy
Editorial: New Insights Into the Complexity of Tumor Immunology in B-Cell Malignancies: Prognostic and Predictive Biomarkers and Therapy
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity
EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia
EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia
TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target
Evaluation of vecabrutinib as a model for noncovalent BTK/ITK inhibition for treatment of chronic lymphocytic leukemia
Phosphoinositide 3-Kinase Signaling in the Tumor Microenvironment: What Do We Need to Consider When Treating Chronic Lymphocytic Leukemia With PI3K Inhibitors?
Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections
An autologous culture model of nodal B-cell lymphoma identifies ex vivo determinants of response to bispecific antibodies
Increased B‐cell activity with consumption of activated monocytes in severe COVID‐19 patients
Clonal evolution in chronic lymphocytic leukemia is scant in relapsed but accelerated in refractory cases after chemo(immune) therapy
IDO1-Targeted Therapy Does Not Control Disease Development in the Eµ-TCL1 Mouse Model of Chronic Lymphocytic Leukemia