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Sagar D. Khare

Rutgers, The State University of New Jersey · US
Area of research
Molecular Biology · Materials Chemistry
Research interest
Research interests include Protein Structure and Dynamics, Enzyme Structure and Function, vaccines and immunoinformatics approaches, and Monoclonal and Polyclonal Antibodies Research.
h-index
36
citations
7,578
works
148
NIH funding
primary concept
email

Recent publications

Electron microscopy holdings of the Protein Data Bank: the impact of the resolution revolution, new validation tools, and implications for the future
Biophysical Reviews 2022cited by 45position: middledoi
Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization
Biochemistry 2022cited by 36position: middledoi
Macromolecular modeling and design in Rosetta: recent methods and frameworks
Nature Methods 2020cited by 908position: middledoi
Computational design of ligand-binding proteins with high affinity and selectivity
Nature 2013cited by 449position: middledoi
Computational Design of an Unnatural Amino Acid Dependent Metalloprotein with Atomic Level Accuracy
Journal of the American Chemical Society 2013cited by 115position: middledoi
Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis
Nature Chemical Biology 2012cited by 209position: firstdoi
Computational Design of Catalytic Dyads and Oxyanion Holes for Ester Hydrolysis
Journal of the American Chemical Society 2012cited by 169position: middledoi

Grants

MFB: Targeting the Dark Proteome by Machine-learning-guided Protein Design
NSF2226816$1,500,0002022–2026PIRePORTER
Collaborative Research: Engineering Hyperstable Enzymes via Computationally Guided Protein Stapling
NSF1929237$285,1202019–2023PIRePORTER
Design Principles of Molecular Computing Using Engineered Enzymes
NSF1716623$300,0002017–2020PIRePORTER
Computational design of novel biodegrative enzyme pathways
NSF1330760$650,0002013–2016PIRePORTER

Frequent collaborators

David Baker · Howard Hughes Medical Institute4 papers (2012–2013)Barry Stoddard · Seattle University3 papers (2012–2013)J. Seetharaman · Columbia University2 papers (2012–2013)Liang Tong · Xi'an University of Science and Technology2 papers (2012–2013) · 2 papers (2012–2012)Scott Lew · Columbia University2 papers (2012–2013)F. Forouhar · Columbia University2 papers (2012–2013)Christine Zardecki · Rutgers, The State University of New Jersey1 papers (2022–2022) · 1 papers (2013–2013)J.P. Bacik · Cornell University1 papers (2022–2022)Jason T. Kaelber · Rutgers, The State University of New Jersey1 papers (2022–2022) · 1 papers (2013–2013)G.T. Montelione · Rutgers, The State University of New Jersey1 papers (2012–2012) · 1 papers (2022–2022)Eric J. Moore · University of Rochester1 papers (2022–2022)Florian Richter · Technische Hochschule Mannheim1 papers (2012–2012)Wei Dai · Rutgers, The State University of New Jersey1 papers (2022–2022)A.P. Kuzin · Columbia University1 papers (2012–2012)Yifan Song · Sinopec (China)1 papers (2012–2012)Jasmine Young · Rutgers, The State University of New Jersey1 papers (2022–2022)