Area of research
Cancer Research · Cardiology and Cardiovascular Medicine
Research interest
Research focused on Cell biology and Gene knockdown, with related work in RNA, Heart failure, Apoptosis. Notable publications include 'Celastrol Attenuates Angiotensin II–Induced Cardiac Remodeling by Targeting STAT3', 'LncRNA ZFAS1 as a SERCA2a Inhibitor to Cause Intracellular Ca 2+ Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction', and 'Reciprocal Changes of Circulating Long Non-Coding RNAs ZFAS1 and CDR1AS Predict Acute Myocardial Infarction'.
Palmitoylated SARM1 targeting P4HA1 promotes collagen deposition and myocardial fibrosis: A new target for anti-myocardial fibrosis
Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activator 1b (Mob1b)
A novel feedback loop: CELF1/circ-CELF1/BRPF3/KAT7 in cardiac fibrosis
CircRNA CDR1AS promotes cardiac ischemia–reperfusion injury in mice by triggering cardiomyocyte autosis
Macrophage-Secreted U2AF1 Orchestrates Coronary Artery Angiogenesis to Facilitate Myocardial Infarction Repair Through the Regulation of Yap1 Variable Splicing
Spexin Diminishes Atrial Fibrillation Vulnerability by Acting on Galanin Receptor 2
Deletion of ASPP1 in myofibroblasts alleviates myocardial fibrosis by reducing p53 degradation
LncRNA CCRR maintains Ca2+ homeostasis against myocardial infarction through the FTO-SERCA2a pathway
Atrial fibrillation variant-to-gene prioritization through cross-ancestry eQTL and single-nucleus multiomic analyses
The effect of macrophage-cardiomyocyte interactions on cardiovascular diseases and development of potential drugs
CCRR regulate MYZAP-PKP2-Nav1.5 signaling pathway in atrial fibrillation following myocardial infarction
Binding of LncDACH1 to dystrophin impairs the membrane trafficking of Nav1.5 protein and increases ventricular arrhythmia susceptibility
Cullin-associated and neddylation-dissociated protein 1 (CAND1) alleviates NAFLD by reducing ubiquitinated degradation of ACAA2
Long non-coding RNA LHX1-DT regulates cardiomyocyte differentiation through H2A.Z-mediated LHX1 transcriptional activation
LncRNA CCRR Attenuates Postmyocardial Infarction Inflammatory Response by Inhibiting the TLR Signalling Pathway
GDF11 promotes wound healing in diabetic mice via stimulating HIF-1ɑ-VEGF/SDF-1ɑ-mediated endothelial progenitor cell mobilization and neovascularization
Research advances on circulating long noncoding RNAs as biomarkers of cardiovascular diseases
Interdependent Nuclear Co-Trafficking of ASPP1 and p53 Aggravates Cardiac Ischemia/Reperfusion Injury
LncRNA-ZFAS1 Promotes Myocardial Ischemia-Reperfusion Injury Through DNA Methylation-Mediated Notch1 Down-Regulation in Mice
NAD+ attenuates cardiac injury after myocardial infarction in diabetic mice through regulating alternative splicing of VEGF in macrophages
Celastrol Attenuates Angiotensin II–Induced Cardiac Remodeling by Targeting STAT3
GDF11 replenishment protects against hypoxia-mediated apoptosis in cardiomyocytes by regulating autophagy
Up‐regulation of miR‐195 contributes to cardiac hypertrophy‐induced arrhythmia by targeting calcium and potassium channels
lncRNA-ZFAS1 induces mitochondria-mediated apoptosis by causing cytosolic Ca2+ overload in myocardial infarction mice model
MicroRNA-132 regulates total protein of Nav1.1 and Nav1.2 in the hippocampus and cortex of rat with chronic cerebral hypoperfusion
LncRNA <i>ZFAS1</i> as a SERCA2a Inhibitor to Cause Intracellular Ca <sup>2+</sup> Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction
Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling
Emodin improves glucose metabolism by targeting microRNA-20b in insulin-resistant skeletal muscle
Anagliptin inhibits neointimal hyperplasia after balloon injury via endothelial cell-specific modulation of SOD-1/RhoA/JNK signaling in the arterial wall
Circulating long non‐coding <scp>RNA</scp>s <i><scp>NRON</scp></i> and <i><scp>MHRT</scp></i> as novel predictive biomarkers of heart failure