Area of research
Molecular Biology · Biomedical Engineering
Research interest
Research interests include Microbial Metabolic Engineering and Bioproduction, Fungal and yeast genetics research, Biofuel production and bioconversion, and Bioinformatics and Genomic Networks.
Systematically exploring yeast metabolism through retrobiosynthesis and deep learning
Reconstruction of human metabolic models with large language models.
A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases
The role of metabolism in shaping enzyme structures over 400 million years
Modular deregulation of central carbon metabolism for efficient xylose utilization in Saccharomyces cerevisiae.
Longitudinal big biological data in the AI era
Longitudinal big biological data in the AI era.
Computational biology predicts metabolic engineering targets for increased production of 103 valuable chemicals in yeast.
Modeling for understanding and engineering metabolism.
Yeast adapts to diverse ecological niches driven by genomics and metabolic reprogramming.
Matrix regulation: a plug-and-tune method for combinatorial regulation in Saccharomyces cerevisiae.
AlphaGEM Enables Precise Genome-Scale Metabolic Modelling by Integrating Protein Structure Alignment with deep-learning-based Dark Metabolism Mining
ChIP-exo and CRISPRi/a illuminate the role of Pdr1 and Yap1 in acetic acid tolerance in <i>Saccharomyces cerevisiae</i>.
Multi-omics characterization of improved cognitive functions in Parkinson's disease patients after the combined metabolic activator treatment: a randomized, double-blinded, placebo-controlled phase II trial.
Author comment: Modeling for understanding and engineering metabolism — R1/PR6
A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases.
AlphaGEM Enables Precise Genome-Scale Metabolic Modelling by Integrating Protein Structure Alignment with Deep-learning-based Dark Metabolism Mining
TRYing to evaluate production costs in microbial biotechnology.
Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer’s disease
Increased CO<sub>2</sub> fixation enables high carbon-yield production of 3-hydroxypropionic acid in yeast.
A bacterial platform for producing aromatic esters from glycerol
De novo production of protoberberine and benzophenanthridine alkaloids through metabolic engineering of yeast.
Brain energy metabolism is optimized to minimize the cost of enzyme synthesis and transport.
Extending the G1 phase improves the production of lipophilic compounds in yeast by boosting enzyme expression and increasing cell size.
Metabolic collaboration between cells in the tumor microenvironment has a negligible effect on tumor growth.
The Role of Metabolism in Shaping Enzyme Structures Over 400 Million Years of Evolution
Yeast adapts to diverse ecological niches driven by genomics and metabolic reprogramming
Discriminating Benign from Malignant Lung Diseases Using Plasma Glycosaminoglycans and Cell-Free DNA.