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John F. Valentine

University of Utah Health Care · US
Area of research
Genetics · Epidemiology
Research interest
Research interests include Inflammatory Bowel Disease, Microscopic Colitis, Marine and fisheries research, and Marine and coastal plant biology.
h-index
49
citations
9,452
works
263
NIH funding
primary concept
Medicine
email

Recent publications

A Randomized Phase II Study of Efmarodocokin Alfa, an interleukin-22 Agonist, Versus Vedolizumab in Patients With Ulcerative Colitis
Clinical Gastroenterology and Hepatology 2024cited by 10position: middledoi
Vedolizumab, Adalimumab, and Methotrexate Combination Therapy in Crohn’s Disease (EXPLORER)
Clinical Gastroenterology and Hepatology 2023cited by 86position: middledoi
Etrolizumab as induction and maintenance therapy in patients with moderately to severely active Crohn's disease (BERGAMOT): a randomised, placebo-controlled, double-blind, phase 3 trial
˜The œLancet. Gastroenterology & hepatology 2022cited by 70position: middledoi
Proactive infliximab optimisation using a pharmacokinetic dashboard versus standard of care in patients with Crohn’s disease: study protocol for a randomised, controlled, multicentre, open-label study (the OPTIMIZE trial)
BMJ Open 2022cited by 29position: middledoi
Metabolic targeting of NRF2 potentiates the efficacy of the TRAP1 inhibitor G-TPP through reduction of ROS detoxification in colorectal cancer
Cancer Letters 2022cited by 22position: middledoi
Postvaccination Symptoms After a Third Dose of mRNA SARS-CoV-2 Vaccination in Patients With Inflammatory Bowel Disease: Results From CORALE-IBD
Inflammatory Bowel Diseases 2022cited by 14position: middledoi
Biodiversity influences the effects of oil disturbance on coastal ecosystems.
2022cited by 7position: contributordoi
A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn’s Disease
Gastroenterology 2021cited by 286position: middledoi
Adaptive immunity induces mutualism between commensal eukaryotes
Nature 2021cited by 202position: middledoi
Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease
The American Journal of Human Genetics 2021cited by 43position: middledoi
Complexities of disturbance response in a marine food web
Limnology and Oceanography 2021cited by 17position: contributordoi
Herbivory in Seagrass Meadows: an Evolving Paradigm
Estuaries and Coasts 2020cited by 28position: contributordoi
501 Trial in progress: VALO study evaluating PTX-022 in adults with moderate-to-severe pachyonychia congenita, a rare, chronically debilitating disease that makes walking difficult or impossible
Journal of Investigative Dermatology 2020cited by 0position: middledoi
Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis
Cell Host & Microbe 2019cited by 600position: middledoi
Methotrexate Is Not Superior to Placebo in Maintaining Steroid-Free Response or Remission in Ulcerative Colitis
Gastroenterology 2018cited by 89position: middledoi
Family History Associates With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases
Clinical Gastroenterology and Hepatology 2018cited by 69position: middledoi
CMV Disease in IBD: Comparison of Diagnostic Tests and Correlation with Disease Outcome
Inflammatory Bowel Diseases 2018cited by 28position: middledoi
Colorectal Cancer in Inflammatory Bowel Diseases: A Population-Based Study in Utah
Digestive Diseases and Sciences 2017cited by 47position: middledoi
Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease
Gastroenterology 2016cited by 158position: middledoi
Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans
Gastroenterology 2015cited by 80position: middledoi
Human Placenta-derived Cells (PDA-001) for the Treatment of Moderate-to-severe Crohnʼs Disease
Inflammatory Bowel Diseases 2015cited by 79position: middledoi
Briakinumab for Treatment of Crohnʼs Disease
Inflammatory Bowel Diseases 2015cited by 76position: middledoi
MicroRNA-146a constrains multiple parameters of intestinal immunity and increases susceptibility to DSS colitis
Oncotarget 2015cited by 54position: middledoi
Use of Humanized Mice to Study the Pathogenesis of Autoimmune and Inflammatory Diseases
Inflammatory Bowel Diseases 2015cited by 45position: middledoi
EMerging BiomARKers in Inflammatory Bowel Disease (EMBARK) Study Identifies Fecal Calprotectin, Serum MMP9, and Serum IL-22 as a Novel Combination of Biomarkers for Crohn's Disease Activity: Role of Cross-Sectional Imaging
The American Journal of Gastroenterology 2013cited by 108position: middledoi
Placental Transfer of Anti–Tumor Necrosis Factor Agents in Pregnant Patients With Inflammatory Bowel Disease
Clinical Gastroenterology and Hepatology 2012cited by 490position: middledoi
Contribution of higher risk genes and European admixture to Crohnʼs disease in African Americans
Inflammatory Bowel Diseases 2012cited by 32position: middledoi

Grants

Collaborative Proposal: Gulf Coast ADVANCE: Cross Institutional Synergy for Women Scientists
NSF1311030$44,6522013–2016PIRePORTER
CAREER: An Energy-Subtraction Compton Scatter Camera for Medical Imaging
NSF9996121$203,2471999–2002PIRePORTER
CAREER: An Energy-Subtraction Compton Scatter Camera for Medical Imaging
NSF9734276$50,0001998–1999PIRePORTER

Frequent collaborators

Mary P. Bronner · University of Utah3 papers (2015–2022)Corey A. Siegel · Dartmouth–Hitchcock Medical Center3 papers (2012–2023) · 3 papers (2020–2022)Bruce E. Sands · Seattle University3 papers (2015–2023)Ryan M. O’Connell · University of Utah3 papers (2015–2021)Brian G. Feagan · Western University3 papers (2013–2023)June L. Round · University of Utah3 papers (2015–2021)Karen Curtin · Bristol Eye Hospital2 papers (2017–2018)W. Zac Stephens · University of Utah2 papers (2019–2021)Douglas C. Wolf · Atlanta Gastroenterology Associates2 papers (2012–2023)Randall W. Burt · University of Utah2 papers (2017–2018)Stephen L. Guthery · University of Utah2 papers (2017–2018)Remo Panaccione · Nutrition-Génétique et Exposition aux Risques Environnementaux2 papers (2015–2022)Stephen B. Hanauer · Northwestern University2 papers (2015–2015)Çharles N. Bernstein · University of Manitoba2 papers (2017–2018)Marla C. Dubinsky · Takeda (Japan)2 papers (2012–2022)Nadim J. Ajami · The University of Texas MD Anderson Cancer Center2 papers (2015–2019)Rickesha Bell · University of Utah2 papers (2019–2021)Yuan Wan · Binghamton University2 papers (2017–2018)William J. Sandborn · Mirati Therapeutics (United States)2 papers (2015–2022)