Area of research
Cancer Research · Rheumatology
Research interest
Research interests include MicroRNA in disease regulation, Rheumatoid Arthritis Research and Therapies, Genetic Associations and Epidemiology, and Cancer-related molecular mechanisms research.
Lower Dose-Normalized Tacrolimus Exposure in CYP3A5*6 vs. *3 Loss-of-Function Allele Carriers: A Longitudinal Retrospective Real-World Study in Kidney Transplant Recipients.
Survival of patients with colorectal or pancreatic cancer who received UGT1A1 genotype-guided dosing of irinotecan in the Netherlands (2017–2024): a retrospective, multicentre cohort study
Evaluation of an interprofessional education program involving medical and pharmacy students: a mixed-method study
The impact of autoantibodies on the efficacy of biological disease-modifying anti-rheumatic drugs in rheumatoid arthritis: meta-analysis of randomized controlled trials.
The effectiveness of pembrolizumab maintenance with or without pemetrexed after induction treatment for advanced non-squamous Non-Small-Cell Lung cancer.
Discovering novel germline genetic variants linked to severe fluoropyrimidine-related toxicity in- and outside DPYD
Clinical characteristics and survival outcomes of patients with primary central nervous system lymphoma treated with high-dose methotrexate-based polychemotherapy and consolidation therapies
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study
Location of joint involvement differentiates rheumatoid arthritis into different clinical subsets
Common genetic variant of GC associated with vitamin D deficiency in a Chinese population in the Netherlands
Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype.
Modelling growth curves of the normal infant’s mandible: 3D measurements using computed tomography
MiRNAs Correlate with HLA Expression in Uveal Melanoma: Both Up- and Downregulation Are Related to Monosomy 3.
Effectiveness of endolymphatic duct blockage versus endolymphatic sac decompression in patients with intractable Ménière's disease: study protocol for a double-blinded, randomised controlled trial.
Changes in healthcare utilisation for paediatric tonsillectomy and adenoidectomy in the Netherlands: a population-based study.
TCTEX1D1 is a genetic modifier of disease progression in Duchenne muscular dystrophy
Identification of pharmacogenetic biomarkers for efficacy of cytoreductive surgery plus hyperthermic intraperitoneal mitomycin C in patients with colorectal peritoneal metastases.
Tamoxifen Pharmacogenetics and Metabolism: Results From the Prospective CYPTAM Study
Novel genetic loci affecting facial shape variation in humans.
Powerful testing via hierarchical linkage disequilibrium in haplotype association studies.
Author response: Novel genetic loci affecting facial shape variation in humans
Ensemble landmarking of 3D facial surface scans
Novel quantitative pigmentation phenotyping enhances genetic association, epistasis, and prediction of human eye colour
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression
Genetic studies of body mass index yield new insights for obesity biology
New genetic loci link adipose and insulin biology to body fat distribution
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels
An Automatic 3D Facial Landmarking Algorithm Using 2D Gabor Wavelets
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age