Area of research
Molecular Biology · Cancer Research
Research interest
Research focused on mTORC1 and PI3K/AKT/mTOR pathway, with related work in Cell biology, Cancer research, Mitochondrial fission. Notable publications include 'mTOR coordinates protein synthesis, mitochondrial activity and proliferation', 'mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1', and 'METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis'.
Dengue virus and Zika virus alter endoplasmic reticulum-mitochondria contact sites to regulate respiration and apoptosis
PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity
EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis
Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1
mTOR-sensitive translation: Cleared fog reveals more trees
mTOR coordinates protein synthesis, mitochondrial activity and proliferation