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Helena Earl

University of Cambridge · GB
Area of research
Cancer Research · Oncology
Research interest
Research interests include Breast Cancer Treatment Studies, Cancer Treatment and Pharmacology, HER2/EGFR in Cancer Research, and Advanced Breast Cancer Therapies.
h-index
61
citations
17,080
works
364
NIH funding
primary concept
Medicine
email

Recent publications

A multi-ancestry genome-wide study of tamoxifen metabolism and breast cancer recurrence
npj Breast Cancer 2026cited by 0position: middledoi
Neoadjuvant PARP inhibitor scheduling in BRCA1 and BRCA2 related breast cancer: PARTNER, a randomized phase II/III trial
Nature Communications 2025cited by 13position: middledoi
Neoadjuvant PARP inhibitor scheduling in BRCA1 and BRCA2 related breast cancer: PARTNER, a randomized phase II/III trial.
2025cited by 6position: contributordoi
Non-inferiority trials: tyranny or good governance? - Authors' reply.
2025cited by 1position: contributordoi
Reduced duration adjuvant trastuzumab in the treatment of patients with HER2-positive breast cancer: a meta-analysis of randomised controlled non-inferiority trials including IPD data.
2025cited by 1position: contributordoi
315P SYNERGIA breast cancer: Automated assessment of tumour-infiltrating lymphocytes
Annals of Oncology 2025cited by 0position: middledoi
The Lancet Breast Cancer Commission
The Lancet 2024cited by 150position: middledoi
The Lancet Breast Cancer Commission.
2024cited by 117position: contributordoi
The PARTNER trial of neoadjuvant olaparib with chemotherapy in triple-negative breast cancer
Nature 2024cited by 46position: lastdoi
The PARTNER trial of neoadjuvant olaparib with chemotherapy in triple-negative breast cancer.
2024cited by 36position: contributordoi
The tyranny of non-inferiority trials.
2024cited by 20position: contributordoi
Safe de-escalation of chemotherapy in HER2-positive early breast cancer.
2024cited by 1position: contributordoi
Abstract CT012: PARTNER Trial: Neoadjuvant olaparib in triple negative breast cancer (TNBC)
Cancer Research 2024cited by 1position: middledoi
Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials.
2023cited by 136position: contributordoi
Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer (UK TACT2; CRUK/05/19): quality of life results from a multicentre, phase 3, open-label, randomised, controlled trial
The Lancet Oncology 2023cited by 14position: middledoi
Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer (UK TACT2; CRUK/05/19): quality of life results from a multicentre, phase 3, open-label, randomised, controlled trial.
2023cited by 10position: contributordoi
Multi-omic machine learning predictor of breast cancer therapy response.
2022cited by 411position: contributordoi
Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients.
2022cited by 361position: contributordoi
The Lancet Breast Cancer Commission: tackling a global health, gender, and equity challenge.
2022cited by 29position: contributordoi
PARTNER: A randomized, phase II/III trial to evaluate the safety and efficacy of the addition of olaparib to platinum-based neoadjuvant chemotherapy in patients with triple-negative and/or germline BRCA-mutated breast cancer.
Journal of Clinical Oncology 2022cited by 7position: middledoi
Magnetization transfer imaging of ovarian cancer: initial experiences of correlation with tissue cellularity and changes following neoadjuvant chemotherapy.
2022cited by 0position: contributordoi
Abstract OT2-24-01: PARTNER: Randomised, phase II/III trial to evaluate the safety and efficacy of the addition of olaparib to platinum-based neoadjuvant chemotherapy in triple negative and/or germline BRCA mutated breast cancer patients
Cancer Research 2022cited by 0position: middledoi
Magnetization transfer imaging of ovarian cancer: initial experiences of correlation with tissue cellularity and changes following neoadjuvant chemotherapy
BJR|Open 2022cited by 0position: middledoi
Abstract CT562: PARTNER: Randomised, phase II/III trial to evaluate the safety and efficacy of the addition of Olaparib to Platinum-based neoadjuvant chemotherapy in triple negative and/or germline BRCA mutated breast cancer patients
Cancer Research 2022cited by 0position: middledoi
Multi-omic machine learning predictor of breast cancer therapy response
Nature 2021cited by 628position: middledoi
LBA11 Individual patient data meta-analysis of 5 non-inferiority RCTs of reduced duration single agent adjuvant trastuzumab in the treatment of HER2 positive early breast cancer
Annals of Oncology 2021cited by 24position: firstdoi
Optimising the Duration of Adjuvant Trastuzumab in Early Breast Cancer in the UK.
2021cited by 2position: contributordoi
Profiteering from vaccine inequity: nudge pharma towards "doing well by doing good".
2021cited by 0position: contributordoi
Baseline Cardiovascular Risk Assessment in Cancer Patients Scheduled to Receive Cardiotoxic Cancer Therapies: A Position Statement and New Risk Assessment Tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in Collaboration with the International Cardio-Oncology Society
European Journal of Heart Failure 2020cited by 749position: middledoi
A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
Nature Communications 2020cited by 47position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Louise Hiller · University of Warwick30 papers (2012–2025)Janet Dunn · University of Warwick26 papers (2012–2022)Carlos Caldas · Concern Foundation22 papers (2012–2022)Jean Abraham · University of Cambridge20 papers (2012–2022)David Cameron · Corewell Health18 papers (2012–2023)Elena Provenzano · Cambridge University Hospitals NHS Foundation Trust18 papers (2013–2025)Anne-Laure Vallier · Diagnostics for the Real World (United Kingdom)15 papers (2013–2022)Andrew Wardley · University of Manchester14 papers (2012–2023)Karen McAdam · Cambridge University Hospitals NHS Foundation Trust11 papers (2013–2022)Luke Hugh-Davies · Cambridge University Hospitals NHS Foundation Trust10 papers (2012–2020)Daniel Rea · Science for Life Laboratory10 papers (2012–2023)David Miles · PsiOxus Therapeutics (United Kingdom)9 papers (2012–2020)James D. Brenton · University of Cambridge9 papers (2012–2022)Paul D.P. Pharoah · University of Thessaly8 papers (2012–2022)John M.S. Bartlett · Edinburgh Cancer Research7 papers (2012–2021)Mercedes Jimenez‐Liñan · Cambridge University Hospitals NHS Foundation Trust7 papers (2012–2022)Tamas Hickish · Dorset HealthCare University NHS Foundation Trust7 papers (2013–2024)Ioannis Gounaris · Merck KGaA, Darmstadt (Germany)7 papers (2013–2017)Jeremy Thomas · NHS Lothian7 papers (2014–2022)Stephen Houston · University of Kansas6 papers (2013–2017)