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Janet L. Smith

University of Michigan–Ann Arbor · US
Area of research
Materials Chemistry · Pharmacology
Research interest
Research focused on RNA and Zinc finger, with related work in Stereochemistry, Flavivirus, Indole test. Notable publications include 'Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction', 'Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences', and 'Function and Structure of MalA/MalA′, Iterative Halogenases for Late-Stage C–H Functionalization of Indole Alkaloids'.
h-index
citations
665
works
9
NIH funding
primary concept
email

Recent publications

Functional anatomy of zinc finger antiviral protein complexes
Nature Communications 2024cited by 12position: middledoi
Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (−)-Eurotiumin A
Journal of the American Chemical Society 2022cited by 38position: middledoi
Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction
Science 2021cited by 153position: middledoi
Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway
Journal of the American Chemical Society 2020cited by 68position: middledoi
Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences
Proceedings of the National Academy of Sciences 2019cited by 150position: lastdoi
Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels–Alderase
Nature Chemistry 2019cited by 79position: middledoi
Sacrificial Cobalt–Carbon Bond Homolysis in Coenzyme B<sub>12</sub> as a Cofactor Conservation Strategy
Journal of the American Chemical Society 2018cited by 30position: middledoi
Function and Structure of MalA/MalA′, Iterative Halogenases for Late-Stage C–H Functionalization of Indole Alkaloids
Journal of the American Chemical Society 2017cited by 80position: middledoi
APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA
Nature Communications 2017cited by 55position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

David H. Sherman · University of Colorado Denver4 papers (2017–2022)William Clay Brown · Case Western Reserve University3 papers (2017–2021)Amy E. Fraley · University of Michigan–Ann Arbor3 papers (2017–2020)Robert M. Williams · University of Colorado Denver3 papers (2017–2020)K. N. Houk · University of California, Los Angeles3 papers (2017–2020)Qingyun Dan · QB33 papers (2017–2022)Paul D. Bieniasz · Rockefeller University3 papers (2017–2024)Jennifer Bohn · Rockefeller University2 papers (2017–2024)Matthew A. Takata · Rockefeller University2 papers (2019–2024)Fengan Yu · University of Michigan2 papers (2019–2020)Jennifer L. Meagher · University of Michigan–Ann Arbor2 papers (2019–2024)Samantha P. Kelly · University of Michigan–Ann Arbor2 papers (2020–2022)Sean A. Newmister · University of Michigan–Ann Arbor2 papers (2019–2020)Vikram V. Shende · Scripps Institution of Oceanography2 papers (2019–2022)Daniel Gonçalves-Carneiro · Imperial College London2 papers (2019–2024)Ashootosh Tripathi · University of Michigan–Ann Arbor1 papers (2017–2017)Jeffrey Li · University of California, Berkeley1 papers (2021–2021)Jamie R. Konwerski · University of Michigan–Ann Arbor1 papers (2021–2021)Nicholas T. N. Lo · University of California, Berkeley1 papers (2021–2021)Scott B. Biering · University of California San Diego1 papers (2021–2021)