Area of research
Molecular Biology · Cell Biology
Research interest
Research focused on Cell biology and Mitochondrion, with related work in Endoplasmic reticulum, Organelle, Parkin. Notable publications include 'Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance', 'PINK1/Parkin Mediated Mitophagy, Ca2+ Signalling, and ER–Mitochondria Contacts in Parkinson’s Disease', and 'Mitochondria Associated Membranes (MAMs): Architecture and physiopathological role'.
A SPLICS reporter reveals $${{{{{\boldsymbol{\alpha }}}}}}$$-synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation
Perturbation of the host cell Ca2+ homeostasis and ER-mitochondria contact sites by the SARS-CoV-2 structural proteins E and M
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance
Mitochondria Associated Membranes (MAMs): Architecture and physiopathological role
Apoptotic signals at the endoplasmic reticulum-mitochondria interface
PINK1/Parkin Mediated Mitophagy, Ca2+ Signalling, and ER–Mitochondria Contacts in Parkinson’s Disease
An expanded palette of improved SPLICS reporters detects multiple organelle contacts in vitro and in vivo
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases
ER–Mitochondria Contact Sites Reporters: Strengths and Weaknesses of the Available Approaches