Area of research
Immunology · Molecular Biology
Research interest
Research interests include Single-cell and spatial transcriptomics, Immune cells in cancer, Atherosclerosis and Cardiovascular Diseases, and T-cell and B-cell Immunology.
Resolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges
Dissecting antibody responses to cardiac receptors in patients with myocardial infarction
Respiratory syncytial virus load-dependent ciliated cell dedifferentiation and downregulation of immune response genes
Single-cell RNA-seq using UltraMarathonRT expands the known transcriptome
The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation
CD8 <sup>+</sup> T Cells Drive Plaque Smooth Muscle Cell Dedifferentiation in Experimental Atherosclerosis
Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells
Characterization of a Human Respiratory Mucosa Model to Study Odorant Metabolism
Characterization and implementation of the MarathonRT template-switching reaction to expand the capabilities of RNA-seq
Human respiratory tissue models to study nasal odorant metabolism
Gewebemodelle der humanen Atemwege zur Untersuchung des nasalen Geruchstoffmetabolismus
Identifying Modulators of Cellular Responses by Heterogeneity-sequencing
Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects
Th17.1 cell driven sarcoidosis-like inflammation after anti-BCMA CAR T cells in multiple myeloma
Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy
Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis
Rapid neutrophil mobilization by VCAM-1+ endothelial cell-derived extracellular vesicles
Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
Nonproductive exposure of PBMCs to SARS‐CoV‐2 induces cell‐intrinsic innate immune responses
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis
Complement activation induces excessive T cell cytotoxicity in severe COVID-19
Interleukin-23 receptor expressing γδ T cells locally promote early atherosclerotic lesion formation and plaque necrosis in mice
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment
Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling
12 Grand Challenges in Single-Cell Data Science
12 Grand challenges in single-cell data science
12 Grand challenges in single-cell data science
12 Grand Challenges in Single-Cell Data Science
Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry
Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes