Area of research
Oncology · Genetics
Research interest
Research interests include Cancer Cells and Metastasis, Digestive system and related health, Colorectal Cancer Treatments and Studies, and Wnt/β-catenin signaling in development and cancer.
Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status
ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer
Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy
ZEB1-dependent modulation of fibroblast polarization governs inflammation and immune checkpoint blockade sensitivity in colorectal cancer
Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer
Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression
Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids
A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer
3D model for <scp>CAR</scp> ‐mediated cytotoxicity using patient‐derived colorectal cancer organoids
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses
Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2–Deficient Intestinal Organoids
Visualization of a short-range Wnt gradient in the intestinal stem-cell niche