Area of research
Electrical and Electronic Engineering · Atomic and Molecular Physics, and Optics
Research interest
Research interests include Solid State Laser Technologies, Laser Design and Applications, Laser-Matter Interactions and Applications, and Cancer Genomics and Diagnostics.
Distinct molecular profiles associated with early vs late genome instability in cancer
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma.
The genomic landscape of 2,023 colorectal cancers
The genomic landscape of 2,023 colorectal cancers.
Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer.
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer.
Immune evasion impacts the landscape of driver genes during cancer evolution.
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer
The temporal evolution of cancer hallmarks
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors.
Phenotypic plasticity and genetic control in colorectal cancer evolution.
The co-evolution of the genome and epigenome in colorectal cancer.
Very large hidden genetic diversity in one single tumor: evidence for tumors-in-tumor
Very large hidden genetic diversity in one single tumor: evidence for tumors-in-tumor.
Immune evasion impacts the selective landscape of driver genes during tumorigenesis
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
Prediction of Benefit from Checkpoint Inhibitors in Mismatch Repair Deficient Metastatic Colorectal Cancer: Role of Tumor Infiltrating Lymphocytes
Subclonal reconstruction of tumors by using machine learning and population genetics.
Evolutionary dynamics of neoantigens in growing tumors.
Prediction of Benefit from Checkpoint Inhibitors in Mismatch Repair Deficient Metastatic Colorectal Cancer: Role of Tumor Infiltrating Lymphocytes.
Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios.
Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells.
The rate and spectrum of mosaic mutations during embryogenesis revealed by RNA sequencing of 49 tissues.
Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking.
<i>dN/dS</i> dynamics quantify tumour immunogenicity and predict response to immunotherapy
Allele balance bias identifies systematic genotyping errors and false disease associations.
Single-cell genetic analysis of clonal dynamics in colorectal adenomas indicates CDX2 gain as a predictor of recurrence.
Model-based tumor subclonal reconstruction