Area of research
Genetics · Ophthalmology
Research interest
Research focused on Macular degeneration and Genome-wide association study, with related work in Biobank, Renal function, Endocrinology. Notable publications include 'Population-based reference values for kidney function and kidney function decline in 25- to 95-year-old Germans without and with diabetes', 'Cellular Pathophysiology of Mutant Voltage-Dependent Ca2+ Channel CACNA1H in Primary Aldosteronism', and 'Genetic-by-age interaction analyses on complex traits in UK Biobank and their potential to identify effects on longitudinal trait change'.
A novel age-informative polygenic score improves predictive ability for kidney function and kidney function decline
Association of high-sensitivity cardiac troponin T with all-cause and cardiovascular mortality in a mobile cohort of older adults aged 70 to 95 years – Results from the AugUR study
NT-proBNP in the very old population: reference values and heart failure specificity from the AugUR-study
Diverse-Ancestry GWAS of Age-Related Macular Degeneration on 16,108 Examined Cases and 18,038 Controls
Large-Scale Gene-Smoking Interactions and Fine Mapping Study Identifies Multiple Novel Blood Pressure Loci in over 1 Million Individuals
The Association of Polygenic Risk Score With Glaucoma and Its Related Traits: Results From Two German Population-Based Studies
Population-based reference values for kidney function and kidney function decline in 25- to 95-year-old Germans without and with diabetes
Genetic-by-age interaction analyses on complex traits in UK Biobank and their potential to identify effects on longitudinal trait change
Nuclear and mitochondrial genetic variants associated with mitochondrial DNA copy number
Analyzing longitudinal trait trajectories using GWAS identifies genetic variants for kidney function decline
Diverse ancestry GWAS for advanced age-related macular degeneration in TOPMed-imputed and Ophthalmologically-confirmed 16,108 cases and 18,038 controls
Photostress Recovery Time as a Potential Predictive Biomarker for Age-Related Macular Degeneration
Genetic Risk Score Analysis Supports a Joint View of Two Classification Systems for Age-Related Macular Degeneration
Polygenic scores for estimated glomerular filtration rate in a population of general adults and elderly – comparative results from the KORA and AugUR study
Cellular Pathophysiology of Mutant Voltage-Dependent Ca2+ Channel CACNA1H in Primary Aldosteronism