Area of research
Biochemistry · Physiology
Research interest
Research interests include Lipid metabolism and biosynthesis, Adipose Tissue and Metabolism, Pancreatic function and diabetes, and Photosynthetic Processes and Mechanisms.
Essential Biology of Lipid Droplets
The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway
The pathogenesis of hepatic steatosis in MASLD: a lipid droplet perspective
Plasma lipidome dysregulation in frontotemporal dementia reveals shared, genotype‐specific, and severity‐linked alterations
A progranulin variant causing childhood interstitial lung disease responsive to anti-TNF-α biologic therapy
PLD3 and PLD4 synthesize S,S-BMP, a key phospholipid enabling lipid degradation in lysosomes
The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets
Structure and function of lipid droplet assembly complexes
Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity
The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification
Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis
Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity
Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity
Seipin forms a flexible cage at lipid droplet formation sites
Identification of two pathways mediating protein targeting from ER to lipid droplets
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology
Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane
Key Factors Governing Initial Stages of Lipid Droplet Formation
An open-access volume electron microscopy atlas of whole cells and tissues
The CYTOLD and ERTOLD pathways for lipid droplet–protein targeting
Conditional targeting of phosphatidylserine decarboxylase to lipid droplets
Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues
The Phase of Fat: Mechanisms and Regulation of Lipid Storage
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency
Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression
Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme
Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting
Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis
A Systematic Protein Turnover Map for Decoding Protein Degradation