Area of research
Hematology · Genetics
Research interest
Research interests include Acute Myeloid Leukemia Research, Myeloproliferative Neoplasms: Diagnosis and Treatment, CAR-T cell therapy research, and Chronic Myeloid Leukemia Treatments.
CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias
Activation of a nongenetic AHR-ELMSAN1 axis optimizes BET-targeting therapy and suppresses leukemia stem cells in preclinical models
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition
Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity
Immune dysfunction signatures predict outcomes and define checkpoint blockade–unresponsive microenvironments in acute myeloid leukemia
IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells
Signatures of immune senescence predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia
The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia
Sirtuin 3 Inhibition Targets AML Stem Cells through Perturbation of Fatty Acid Oxidation
The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia
Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia
Impact of High-Molecular-Risk Mutations on Transplantation Outcomes in Patients with Myelofibrosis
Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia
Immune Landscapes Predict Chemotherapy Resistance and Anti-Leukemic Activity of Flotetuzumab, an Investigational CD123×CD3 Bispecific Dart® Molecule, in Patients with Relapsed/Refractory Acute Myeloid Leukemia
Sensitive tumour detection and classification using plasma cell-free DNA methylomes
CD123 target validation and preclinical evaluation of ADCC activity of anti-CD123 antibody CSL362 in combination with NKs from AML patients in remission
A 17-gene stemness score for rapid determination of risk in acute leukaemia
Innate Immune Dysfunctions in Aged Mice Facilitate the Systemic Dissemination of Methicillin-Resistant S. aureus