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Paul B. Chapman

Weill Cornell Medicine · US
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Area of research
Oncology · Molecular Biology
Research interest
Research interests include Melanoma and MAPK Pathways, Cutaneous Melanoma Detection and Management, Immunotherapy and Immune Responses, and Cancer Immunotherapy and Biomarkers.
h-index
74
citations
43,886
works
516
NIH funding
primary concept
Medicine
email

Recent publications

Management of immune-related cutaneous adverse events with dupilumab
Journal for ImmunoTherapy of Cancer 2023cited by 46position: middledoi
Ipilimumab alone or in combination with nivolumab in patients with advanced melanoma who have progressed or relapsed on PD-1 blockade: clinical outcomes and translational biomarker analyses
Journal for ImmunoTherapy of Cancer 2022cited by 45position: middledoi
The State of Melanoma: Emergent Challenges and Opportunities
Clinical Cancer Research 2021cited by 107position: middledoi
LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade
Science Translational Medicine 2021cited by 97position: middledoi
Therapeutic Implications of Detecting MAPK-Activating Alterations in Cutaneous and Unknown Primary Melanomas
Clinical Cancer Research 2021cited by 52position: middledoi
Long-Term Outcomes and Responses to Retreatment in Patients With Melanoma Treated With PD-1 Blockade
Journal of Clinical Oncology 2020cited by 190position: lastdoi
Long-term outcomes in patients with BRAF V600-mutant metastatic melanoma receiving dabrafenib monotherapy: Analysis from phase 2 and 3 clinical trials
European Journal of Cancer 2020cited by 69position: lastdoi
Immune Checkpoint Inhibitor-Associated Optic Neuritis
Ophthalmology 2020cited by 60position: middledoi
Safety and efficacy of combination nivolumab plus ipilimumab in patients with advanced melanoma: results from a North American expanded access program (CheckMate 218)
Melanoma Research 2020cited by 23position: middledoi
A phase II study to evaluate the need for > two doses of nivolumab + ipilimumab combination (combo) immunotherapy.
Journal of Clinical Oncology 2020cited by 19position: lastdoi
Treatment Outcomes of Immune-Related Cutaneous Adverse Events
Journal of Clinical Oncology 2019cited by 234position: middledoi
Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis
The Lancet Oncology 2018cited by 655position: middledoi
Peripheral blood clinical laboratory variables associated with outcomes following combination nivolumab and ipilimumab immunotherapy in melanoma
Cancer Medicine 2018cited by 127position: middledoi
Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer
Cancer Cell 2018cited by 109position: middledoi
Vemurafenib in patients with BRAFV600 mutation-positive metastatic melanoma: final overall survival results of the randomized BRIM-3 study
Annals of Oncology 2017cited by 257position: firstdoi
Measuring Toxic Effects and Time to Treatment Failure for Nivolumab Plus Ipilimumab in Melanoma
JAMA Oncology 2017cited by 162position: lastdoi
Clinical and Morphologic Characteristics of MEK Inhibitor–Associated Retinopathy
Ophthalmology 2017cited by 134position: middledoi
Dual MEK/AKT inhibition with trametinib and <scp>GSK</scp>2141795 does not yield clinical benefit in metastatic <scp>NRAS</scp>‐mutant and wild‐type melanoma
Pigment Cell & Melanoma Research 2017cited by 62position: middledoi
Patterns and Timing of Initial Relapse in Pathologic Stage II Melanoma Patients
Annals of Surgical Oncology 2016cited by 55position: middledoi
A randomized phase 2 study of trametinib with or without GSK2141795 in patients with advanced uveal melanoma.
Journal of Clinical Oncology 2016cited by 54position: middledoi
Efficacy and safety of checkpoint blockade for treatment of advanced melanoma (mel) in patients (pts) age 80 and older (80+).
Journal of Clinical Oncology 2016cited by 47position: middledoi
Melanoma and immunotherapy bridge 2015
Journal of Translational Medicine 2016cited by 24position: middledoi
Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center
Journal of Clinical Oncology 2015cited by 1,070position: lastdoi
Phase II Study of Nilotinib in Melanoma Harboring KIT Alterations Following Progression to Prior KIT Inhibition
Clinical Cancer Research 2015cited by 141position: middledoi
Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation
Nature Communications 2015cited by 115position: middledoi
Long-term outcome in BRAFV600E melanoma patients treated with vemurafenib: Patterns of disease progression and clinical management of limited progression
European Journal of Cancer 2015cited by 78position: middledoi
A Retrospective Evaluation of Vemurafenib as Treatment for BRAF-Mutant Melanoma Brain Metastases
The Oncologist 2015cited by 59position: lastdoi
Pilot Trial of Selecting Molecularly Guided Therapy for Patients with Non–V600 BRAF-Mutant Metastatic Melanoma: Experience of the SU2C/MRA Melanoma Dream Team
Molecular Cancer Therapeutics 2015cited by 27position: middledoi
Safety and efficacy of vemurafenib in BRAFV600E and BRAFV600K mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study
The Lancet Oncology 2014cited by 977position: middledoi
Effect of Selumetinib vs Chemotherapy on Progression-Free Survival in Uveal Melanoma
JAMA 2014cited by 425position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Jedd D. Wolchok · Cornell University16 papers (2012–2022)Katherine S. Panageas · Bayer (Germany)14 papers (2013–2022)Margaret K. Callahan · Cornell University13 papers (2012–2022)Michael A. Postow · Memorial Sloan Kettering Cancer Center12 papers (2014–2022)Alexander N. Shoushtari · Humboldt-Universität zu Berlin10 papers (2016–2022)Axel Hauschild · Princess Alexandra Hospital8 papers (2012–2020)Antoni Ribas · UCLA Medical Center8 papers (2012–2022)David B. Solit · New York Oncology Hematology7 papers (2012–2021)Parisa Momtaz · Kettering University7 papers (2015–2021)Richard D. Carvajal · Northwell Health6 papers (2013–2016)Jeffrey A. Sosman · Northwestern University6 papers (2012–2017)Christian U. Blank · Dutch Cancer Society5 papers (2012–2020)Vicki Goodman · Bristol-Myers Squibb (United States)5 papers (2012–2013)Taha Merghoub · Cornell University5 papers (2012–2021)Lev Demidov · Humboldt-Universität zu Berlin5 papers (2012–2020)Ralf Gutzmer · University of Duisburg-Essen5 papers (2012–2020)Keith T. Flaherty · Boston Medical Center5 papers (2012–2017)Mary Guckert · Janssen (United States)5 papers (2012–2013)Neal Rosen · Memorial Sloan Kettering Cancer Center5 papers (2012–2021)Allison Betof Warner · Stanford University5 papers (2018–2021)
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