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Nikolas Pontikos

Moorfields Eye Hospital NHS Foundation Trust · GB
Area of research
Radiology, Nuclear Medicine and Imaging · Ophthalmology
Research interest
Research interests include Retinal Diseases and Treatments, Retinal Development and Disorders, Retinal Imaging and Analysis, and Corneal surgery and disorders.
h-index
43
citations
7,910
works
260
NIH funding
primary concept
Medicine
email

Recent publications

Machine learning derived retinal pigment score from ophthalmic imaging shows ethnicity is not biology
Nature Communications 2025cited by 12position: middledoi
Prevalence and demographics of 331 rare diseases and associated COVID-19-related mortality among 58 million individuals: a nationwide retrospective observational study
The Lancet Digital Health 2025cited by 12position: middledoi
Retinograd-AI: An Open-Source Automated Fundus Autofluorescence Retinal Image Gradability Assessment for Inherited Retinal Diseases
Ophthalmology Science 2025cited by 1position: middledoi
The evolving genetic landscape of telomere biology disorder dyskeratosis congenita
EMBO Molecular Medicine 2024cited by 28position: middledoi
A foundation model for generalizable disease detection from retinal images
Nature 2023cited by 792position: middledoi
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility
Nature Genetics 2022cited by 182position: middledoi
The GA4GH Phenopacket schema defines a computable representation of clinical data
Nature Biotechnology 2022cited by 109position: middledoi
UK Biobank retinal imaging grading: methodology, baseline characteristics and findings for common ocular diseases
Eye 2022cited by 35position: middledoi
Electrical responses from human retinal cone pathways associate with a common genetic polymorphism implicated in myopia
Proceedings of the National Academy of Sciences 2022cited by 32position: middledoi
A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus
Communications Biology 2021cited by 90position: middledoi
Machine Learning Algorithms to Detect Subclinical Keratoconus: Systematic Review
JMIR Medical Informatics 2021cited by 43position: lastdoi
KCNV2-Associated Retinopathy: Detailed Retinal Phenotype and Structural Endpoints—KCNV2 Study Group Report 2
American Journal of Ophthalmology 2021cited by 28position: middledoi
Genetic Basis of Inherited Retinal Disease in a Molecularly Characterized Cohort of More Than 3000 Families from the United Kingdom
Ophthalmology 2020cited by 252position: firstdoi
The X-linked retinopathies: Physiological insights, pathogenic mechanisms, phenotypic features and novel therapies
Progress in Retinal and Eye Research 2020cited by 147position: middledoi
The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants
Nature Communications 2020cited by 115position: middledoi
An Improved Phenotype-Driven Tool for Rare Mendelian Variant Prioritization: Benchmarking Exomiser on Real Patient Whole-Exome Data
Genes 2020cited by 68position: middledoi
The genetic landscape of crystallins in congenital cataract
Orphanet Journal of Rare Diseases 2020cited by 47position: middledoi
KCNV2-Associated Retinopathy: Genetics, Electrophysiology, and Clinical Course—KCNV2 Study Group Report 1
American Journal of Ophthalmology 2020cited by 32position: middledoi
Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study
JAMA Ophthalmology 2019cited by 66position: middledoi
Clinical and Molecular Characterization of Familial Exudative Vitreoretinopathy Associated With Microcephaly
American Journal of Ophthalmology 2019cited by 36position: middledoi
Functional variants in the <i>LRRK2</i> gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease
Science Translational Medicine 2018cited by 405position: middledoi
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population
PLoS Genetics 2018cited by 95position: middledoi
Association of Steroid 5α-Reductase Type 3 Congenital Disorder of Glycosylation With Early-Onset Retinal Dystrophy
JAMA Ophthalmology 2017cited by 53position: middledoi
The Human Phenotype Ontology in 2017
Nucleic Acids Research 2016cited by 800position: middledoi
Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium
Scientific Reports 2016cited by 288position: middledoi
Mutations in REEP6 Cause Autosomal-Recessive Retinitis Pigmentosa
The American Journal of Human Genetics 2016cited by 131position: middledoi
Mutations in CPAMD8 Cause a Unique Form of Autosomal-Recessive Anterior Segment Dysgenesis
The American Journal of Human Genetics 2016cited by 74position: middledoi
A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF
Gastroenterology 2016cited by 67position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Michel Michaelides · Twitter (United States)8 papers (2016–2025)Andrew R. Webster · The London College7 papers (2017–2025)Anthony T. Moore · Cambridge University Hospitals NHS Foundation Trust7 papers (2016–2020)Gavin Arno · Moorfields Eye Hospital NHS Foundation Trust5 papers (2017–2020)Omar A. Mahroo · St Thomas' Hospital4 papers (2020–2025)Alison J. Hardcastle · 4 papers (2016–2021)Pirro G. Hysi · Moorfields Eye Hospital NHS Foundation Trust3 papers (2019–2022)Alice E. Davidson · University of London3 papers (2016–2021)Mariya Moosajee · Moorfields Eye Hospital NHS Foundation Trust2 papers (2020–2025)Christopher J. Hammond · St Thomas' Hospital2 papers (2019–2022) · 2 papers (2019–2020) · 2 papers (2019–2021) · 2 papers (2020–2025)Konstantinos Balaskas · National Institute for Health Research2 papers (2021–2025)Stephen J. Tuft · University of London2 papers (2019–2021) · 2 papers (2019–2021)Ismail Moghul · Moorfields Eye Hospital NHS Foundation Trust2 papers (2021–2025)Sarah Hull · Imperial College Healthcare NHS Trust2 papers (2017–2019) · 2 papers (2019–2020)Michalis Georgiou · University of Arkansas for Medical Sciences2 papers (2020–2020)