Area of research
Cell Biology · Oncology
Research interest
Research interests include Microtubule and mitosis dynamics, Cancer Immunotherapy and Biomarkers, Cancer, Hypoxia, and Metabolism, and Immune cells in cancer.
Gut dysbiosis conveys psychological stress to activate LRP5/β-catenin pathway promoting cancer stemness
SARM1 senses dsDNA to promote NAD+ degradation and cell death
Discovery of a Potent and Highly Selective Inhibitor of Aurora A Kinase
Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
Microbiota enterotoxigenic <i>Bacteroides fragilis</i>-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1
IL1R2 Blockade Alleviates Immunosuppression and Potentiates Anti-PD-1 Efficacy in Triple-Negative Breast Cancer
Tumor-associated macrophage subtypes on cancer immunity along with prognostic analysis and SPP1-mediated interactions between tumor cells and macrophages
Crosstalk between lipid metabolism and EMT: emerging mechanisms and cancer therapy
STAT5 promotes PD-L1 expression by facilitating histone lactylation to drive immunosuppression in acute myeloid leukemia
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model
The suppression of cervical cancer ferroptosis by macrophages: The attenuation of ALOX15 in cancer cells by macrophages-derived exosomes
Chronic stress in solid tumor development: from mechanisms to interventions
Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
Spermine enhances antiviral and anticancer responses by stabilizing DNA binding with the DNA sensor cGAS
Low-density lipoprotein receptor promotes crosstalk between cell stemness and tumor immune microenvironment in breast cancer: a large data-based multi-omics study
Pyrroline-5-carboxylate reductase 1 reprograms proline metabolism to drive breast cancer stemness under psychological stress
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation
Nuclear Aurora kinase A switches m6A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4
cGAS/STING cross-talks with cell cycle and potentiates cancer immunotherapy
MRNIP condensates promote DNA double-strand break sensing and end resection
Targeting lipid metabolism for ferroptotic cancer therapy
A Temporal PROTAC Cocktail‐Mediated Sequential Degradation of AURKA Abrogates Acute Myeloid Leukemia Stem Cells
DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0
Identification of ferroptosis-related signature with potential implications in prognosis and immunotherapy of renal cell carcinoma
VLDLR disturbs quiescence of breast cancer stem cells in a ligand-independent function
PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer
Nuclear Aurora kinase A triggers programmed death‐ligand 1‐mediated immune suppression by activating MYC transcription in triple‐negative breast cancer
CRISPR screening identifies CDK12 as a conservative vulnerability of prostate cancer
Allele frequency deviation (AFD) as a new prognostic model to predict overall survival in lung adenocarcinoma (LUAD)
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells