Area of research
Pharmacology · Experimental and Cognitive Psychology
Research interest
Research interests include Treatment of Major Depression, Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes, Tryptophan and brain disorders, and Mental Health Research Topics.
Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ASCERTAIN-TRD) a randomized clinical trial
Efficacy and Safety of Esmethadone (REL-1017) in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants
Using Drift Diffusion and RL Models to Disentangle Effects of Depression On Decision-Making vs. Learning in the Probabilistic Reward Task.
Rationale and Design for the BLOCK-SAH Study (Pterygopalatine Fossa Block as an Opioid-Sparing Treatment for Acute Headache in Aneurysmal Subarachnoid Hemorrhage): A Phase II, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial with a Sequential Parallel Comparison Design
EEG measures of brain arousal in relation to symptom improvement in patients with major depressive disorder: Results from a randomized placebo-controlled clinical trial.
The future of psychopharmacology: a critical appraisal of ongoing phase 2/3 trials, and of some current trends aiming to de‐risk trial programmes of novel agents
Esmethadone-HCl (REL-1017): a promising rapid antidepressant
Clinical response to EPA supplementation in patients with major depressive disorder is associated with higher plasma concentrations of pro-resolving lipid mediators
Individuals with depression exhibiting a pro-inflammatory phenotype receiving omega-3 polyunsaturated fatty acids experience improved motivation-related cognitive function: Preliminary results from a randomized controlled trial
Efficacy and Safety of AXS-05 (Dextromethorphan-Bupropion) in Patients With Major Depressive Disorder
International pooled patient-level meta-analysis of ketamine infusion for depression: In search of clinical moderators
Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation
Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors
Esmethadone (REL-1017) and Other Uncompetitive NMDAR Channel Blockers May Improve Mood Disorders via Modulation of Synaptic Kinase-Mediated Signaling
Vortioxetine Versus Placebo for Major Depressive Disorder
The effect of single administration of intravenous ketamine augmentation on suicidal ideation in treatment-resistant unipolar depression: Results from a randomized double-blind study
Transitioning From In-Person to Remote Clinical Research on Depression and Traumatic Brain Injury During the COVID-19 Pandemic: Study Modifications and Preliminary Feasibility From a Randomized Controlled Pilot Study.
Transitioning From In-Person to Remote Clinical Research on Depression and Traumatic Brain Injury During the COVID-19 Pandemic: Study Modifications and Preliminary Feasibility From a Randomized Controlled Pilot Study (Preprint)
An electroencephalographic signature predicts antidepressant response in major depression
A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don’t work well enough?
Dose- and time-dependent increase in circulating anti-inflammatory and pro-resolving lipid mediators following eicosapentaenoic acid supplementation in patients with major depressive disorder and chronic inflammation
Double-Blind, Placebo-Controlled, Proof-Of-Concept Trial of a Kappa-Selective Opioid Receptor Antagonist Augmentation in Treatment-Resistant Depression
Anger attacks are associated with persistently elevated irritability in MDD: findings from the EMBARC study
PET imaging of neurotransmission using direct parametric reconstruction.
Brain regulation of emotional conflict predicts antidepressant treatment response for depression.
Time to relapse after a single administration of intravenous ketamine augmentation in unipolar treatment-resistant depression
Efficacy and Tolerability of Adjunctive Intravenous Sodium Nitroprusside Treatment for Outpatients With Schizophrenia
Elevated Amygdala Activity in Young Adults With Familial Risk for Depression: A Potential Marker of Low Resilience
Increased amygdala-visual cortex connectivity in youth with persecutory ideation
Vortioxetine for attention deficit hyperactivity disorder in adults: A randomized, double-blind, placebo-controlled, proof-of-concept study.