Area of research
Oncology · Immunology
Research interest
Research interests include Pancreatic and Hepatic Oncology Research, Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, and Cancer Genomics and Diagnostics.
Pancreatic cancer–restricted cryptic antigens are targets for T cell recognition
A prime editor mouse to model a broad spectrum of somatic mutations in vivo
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution
Deciphering the immunopeptidome in vivo reveals new tumour antigens
Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
Abstract PO-063: Functional interrogation of immune escape in neoantigen-expressing pancreatic cancer identifies a critical role for the CD155/TIGIT axis
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression
Accurate and sensitive quantification of protein-DNA binding affinity
Quantitative Analysis of the DNA Methylation Sensitivity of Transcription Factor Complexes
The p53 C Terminus Controls Site-Specific DNA Binding and Promotes Structural Changes within the Central DNA Binding Domain
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway