Area of research
Molecular Biology · Epidemiology
Research interest
Research focused on Autophagy and AMPK, with related work in Gene silencing, P70-S6 Kinase 1, Cell biology. Notable publications include 'miR-146b-5p inhibits glioma migration and invasion by targeting MMP16', 'TRPV1 activation prevents nonalcoholic fatty liver through UCP2 upregulation in mice', and 'Activation of TGF-β-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy'.
Influenza A virus infection activates caspase-8 to enhance innate antiviral immunity by cleaving CYLD and blocking TAK1 and RIG-I deubiquitination
A77 1726, the active metabolite of the anti‐rheumatoid arthritis drug leflunomide, inhibits influenza A virus replication in vitro and in vivo by inhibiting the activity of Janus kinases
The <scp>Gli1‐Snail</scp> axis contributes to <i>Salmonella</i> Typhimurium‐induced disruption of intercellular junctions of intestinal epithelial cells
Toll‐like receptor signalling cross‐activates the autophagic pathway to restrict<i>Salmonella</i>Typhimurium growth in macrophages
Activation of TGF-β-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy
Inhibition of p70 S6 kinase activity by A77 1726 induces autophagy and enhances the degradation of superoxide dismutase 1 (SOD1) protein aggregates
Inhibition of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation
miR-29s inhibit the malignant behavior of U87MG glioblastoma cell line by targeting DNMT3A and 3B
miR-146b-5p inhibits glioma migration and invasion by targeting MMP16
TRPV1 activation prevents nonalcoholic fatty liver through UCP2 upregulation in mice