Area of research
Materials Chemistry · Computational Theory and Mathematics
Research interest
Research interests include Enzyme Structure and Function, Computational Drug Discovery Methods, Metabolism and Genetic Disorders, and Protein Structure and Dynamics.
Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction
Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor
The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans