Area of research
Immunology · Radiology, Nuclear Medicine and Imaging
Research interest
Research focused on Somatic hypermutation and Repertoire, with related work in Genetics, Antibody, Germline. Notable publications include 'Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data', 'B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes', and 'Models of Somatic Hypermutation Targeting and Substitution Based on Synonymous Mutations from High-Throughput Immunoglobulin Sequencing Data'.
The human IG heavy chain constant gene locus is enriched for large structural variants and coding polymorphisms that vary among human populations
AIRR-C IG Reference Sets: curated sets of immunoglobulin heavy and light chain germline genes
AIRR community curation and standardised representation for immunoglobulin and T cell receptor germline sets
Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma
A BALB/c IGHV Reference Set, Defined by Haplotype Analysis of Long-Read VDJ-C Sequences From F1 (BALB/c x C57BL/6) Mice
A BALB/c IGHV Reference Set, defined by haplotype analysis of long-read VDJ-C sequences from F1 (BALB/c / C57BL/6) mice
Decomposition of Individual SNP Patterns from Mixed DNA Samples
Diversity in immunogenomics: the value and the challenge
Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors
Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming
OGRDB: a reference database of inferred immune receptor genes
System-wide Analysis of the T Cell Response
Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data
Species survival emerge from rare events of individual migration
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes
High-resolution antibody dynamics of vaccine-induced immune responses
Models of Somatic Hypermutation Targeting and Substitution Based on Synonymous Mutations from High-Throughput Immunoglobulin Sequencing Data
Multiple Transcription Factor Binding Sites Predict AID Targeting in Non-Ig Genes