Area of research
Ecology · Molecular Biology
Research interest
Research focused on Glycoconjugate and Burkholderia pseudomallei, with related work in Microbiology, Melioidosis, Streptococcus pneumoniae. Notable publications include 'Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis', 'Recent advances in the production of recombinant glycoconjugate vaccines', and 'Genome-Wide Saturation Mutagenesis of Burkholderia pseudomallei K96243 Predicts Essential Genes and Novel Targets for Antimicrobial Development'.
Immunological and pathobiological characteristics of a novel live Salmonella Typhimurium-vectored Campylobacter vaccine candidate for layer chickens
Evaluation of a FlpA Glycoconjugate Vaccine with Ten N-Heptasaccharide Glycan Moieties to reduce Campylobacter jejuni Colonisation in Chickens
Investigation into the efficiency of diverse <i>N</i> ‐linking oligosaccharyltransferases for glycoengineering using a standardised cell‐free assay
Development of a novel glycoengineering platform for the rapid production of conjugate vaccines
Engineering a suite of E. coli strains for enhanced expression of bacterial polysaccharides and glycoconjugate vaccines
PglB function and glycosylation efficiency is temperature dependent when the pgl locus is integrated in the Escherichia coli chromosome
Use of Precision-Cut Tissue Slices as a Translational Model to Study Host-Pathogen Interaction
Multivalent poultry vaccine development using Protein Glycan Coupling Technology
Evaluation of a Campylobacter jejuni N-glycan-ExoA glycoconjugate vaccine to reduce C. jejuni colonisation in chickens
Rationally designed mariner vectors for functional genomic analysis of Actinobacillus pleuropneumoniae and other Pasteurellaceae species by transposon-directed insertion-site sequencing (TraDIS)
Characterization of Posttranslationally Modified Multidrug Efflux Pumps Reveals an Unexpected Link between Glycosylation and Antimicrobial Resistance
Evaluation of Glycosylated FlpA and SodB as Subunit Vaccines Against Campylobacter jejuni Colonisation in Chickens
Ferric Citrate Regulator FecR Is Translocated across the Bacterial Inner Membrane via a Unique Twin-Arginine Transport-Dependent Mechanism
Recent advances in the production of recombinant glycoconjugate vaccines
Quantitative Analyses Reveal Novel Roles for <i>N-</i> Glycosylation in a Major Enteric Bacterial Pathogen
Cytoplasmic glycoengineering of Apx toxin fragments in the development of Actinobacillus pleuropneumoniae glycoconjugate vaccines
Publisher Correction: Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis
Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine
An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia
Structure-activity relationships in a new class of non-substrate-like covalent inhibitors of the bacterial glycosyltransferase LgtC
Inactivation of bpsl1039-1040 ATP-binding cassette transporter reduces intracellular survival in macrophages, biofilm formation and virulence in the murine model of Burkholderia pseudomallei infection
The <i>N</i> -linking glycosylation system from <i>Actinobacillus pleuropneumoniae</i> is required for adhesion and has potential use in glycoengineering
Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis
Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei
Identification of <i>dfrA14</i> in two distinct plasmids conferring trimethoprim resistance in <i>Actinobacillus pleuropneumoniae</i>
Functional analysis of N-linking oligosaccharyl transferase enzymes encoded by deep-sea vent proteobacteria
Genome-Wide Saturation Mutagenesis of Burkholderia pseudomallei K96243 Predicts Essential Genes and Novel Targets for Antimicrobial Development
Galleria mellonella is an effective model to study Actinobacillus pleuropneumoniae infection
Hijacking bacterial glycosylation for the production of glycoconjugates, from vaccines to humanised glycoproteins
Exploitation of bacterial<i>N</i>-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against<i>Francisella tularensis</i>