Area of research
Molecular Biology · Pathology and Forensic Medicine
Research interest
Research interests include Bone Metabolism and Diseases, Vitamin D Research Studies, Wnt/β-catenin signaling in development and cancer, and Bone health and treatments.
Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells
The gut microbiota is a transmissible determinant of skeletal maturation
Parathyroid hormone–dependent bone formation requires butyrate production by intestinal microbiota
PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells
The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression
IL-17 Receptor Signaling in Osteoblasts/Osteocytes Mediates PTH-Induced Bone Loss and Enhances Osteocytic RANKL Production
Regulatory T cells are expanded by Teriparatide treatment in humans and mediate intermittent PTH‐induced bone anabolism in mice
Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics
Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency
IL-17A Is Increased in Humans with Primary Hyperparathyroidism and Mediates PTH-Induced Bone Loss in Mice
T Cell–Expressed CD40L Potentiates the Bone Anabolic Activity of Intermittent PTH Treatment
The Sclerostin-Independent Bone Anabolic Activity of Intermittent PTH Treatment Is Mediated by T-Cell–Produced Wnt10b
Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B
Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH
PTH expands short-term murine hemopoietic stem cells through T cells