Area of research
Hematology · Immunology
Research interest
Research interests include Platelet Disorders and Treatments, Complement system in diseases, Blood groups and transfusion, and Blood Coagulation and Thrombosis Mechanisms.
Trained immunity causes myeloid cell hypercoagulability.
R1205H (Vicenza) causes conformational changes in the von Willebrand factor D′D3 domains and enhances von Willebrand factor binding to clearance receptors LRP1 and SR-AI
Sustained VWF-ADAMTS-13 axis imbalance and endotheliopathy in long COVID syndrome is related to immune dysfunction
Breast cancer cells mediate endothelial cell activation, promoting von Willebrand factor release, tumor adhesion, and transendothelial migration.
The role of VWF/FVIII in thrombosis and cancer progression in multiple myeloma and other hematological malignancies.
Persistent endotheliopathy in the pathogenesis of long COVID syndrome - Reply to comment from von Meijenfeldt et al.
Persistent endotheliopathy in the pathogenesis of long COVID syndrome
Prolonged elevation of D-dimer levels in convalescent COVID-19 patients is independent of the acute phase response.
Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID-19): evidence of acute and sustained endothelial cell activation.
ADAMTS13 regulation of VWF multimer distribution in severe COVID-19.
The role of von Willebrand factor in breast cancer metastasis.
Management of elective procedures in low von Willebrand factor patients in the LoVIC study.
The relationship between ABO blood group, von Willebrand factor, and primary hemostasis.
Von Willebrand factor and cancer; metastasis and coagulopathies.
Investigating the clearance of VWF A-domains using site-directed PEGylation and novel N-linked glycosylation.
Advances in understanding the molecular mechanisms that maintain normal haemostasis.
von Willebrand factor promotes wound healing.
A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria