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Katie E. Lacy

King's College London · GB
Area of research
Immunology · Oncology
Research interest
Research interests include Immunotherapy and Immune Responses, T-cell and B-cell Immunology, Cancer Immunotherapy and Biomarkers, and Monoclonal and Polyclonal Antibodies Research.
h-index
32
citations
4,059
works
87
NIH funding
primary concept
email

Recent publications

Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4
Nature Communications 2023cited by 40position: middledoi
B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma
Nature Communications 2023cited by 38position: middledoi
Clinical and Translational Significance of Basophils in Patients with Cancer
Cells 2022cited by 41position: middledoi
Enriched circulating and tumor-resident TGF-β <sup>+</sup> regulatory B cells in patients with melanoma promote FOXP3 <sup>+</sup> Tregs
OncoImmunology 2022cited by 38position: middledoi
Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action
European Journal of Immunology 2021cited by 195position: middledoi
Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer
Cancer Research 2021cited by 97position: middledoi
B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies
Frontiers in Immunology 2021cited by 68position: middledoi
A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma
Cancers 2020cited by 38position: middledoi
Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma
Frontiers in Immunology 2019cited by 249position: middledoi
IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states
EBioMedicine 2019cited by 79position: middledoi
Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types
Frontiers in Immunology 2018cited by 138position: middledoi
Skin resident memory CD8+ T cells are phenotypically and functionally distinct from circulating populations and lack immediate cytotoxic function
Clinical & Experimental Immunology 2018cited by 38position: middledoi
BRAF inhibitors: resistance and the promise of combination treatments for melanoma
Oncotarget 2017cited by 112position: middledoi
Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase–induced inflammation
Journal of Allergy and Clinical Immunology 2017cited by 104position: middledoi
B cells and the humoral response in melanoma: The overlooked players of the tumor microenvironment
OncoImmunology 2017cited by 68position: middledoi
IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin
Scientific Reports 2016cited by 69position: middledoi
PAK4 suppresses PDZ-RhoGEF activity to drive invadopodia maturation in melanoma cells
Oncotarget 2016cited by 32position: middledoi
Revisiting the role of B cells in skin immune surveillance
Trends in Immunology 2015cited by 87position: lastdoi
Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma
OncoImmunology 2015cited by 68position: middledoi
Effects of <i>BRAF</i> Mutations and <i>BRAF</i> Inhibition on Immune Responses to Melanoma
Molecular Cancer Therapeutics 2014cited by 84position: middledoi
Antibody therapies for melanoma: New and emerging opportunities to activate immunity (Review)
Oncology Reports 2014cited by 54position: middledoi
IgG4 subclass antibodies impair antitumor immunity in melanoma
Journal of Clinical Investigation 2013cited by 235position: middledoi
Varicella Zoster–Specific CD4+Foxp3+ T Cells Accumulate after Cutaneous Antigen Challenge in Humans
The Journal of Immunology 2013cited by 61position: middledoi
Investigation of the cutaneous response to recall antigen in humans<i>in vivo</i>
Clinical & Experimental Immunology 2013cited by 41position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sophia N. Karagiannis · Guy's Hospital16 papers (2013–2022)James Spicer · King's College London13 papers (2013–2022)Silvia Crescioli · King's College London10 papers (2016–2022)Debra H. Josephs · Guy's Hospital9 papers (2013–2022)Anthony Cheung · King's College London8 papers (2016–2022)Ciaran Healy · St Thomas' Hospital7 papers (2013–2022)Jenny L. C. Geh · St Thomas' Hospital7 papers (2013–2022)Frank O. Nestlé · St Thomas' Hospital7 papers (2013–2018)Heather J. Bax · King's College London7 papers (2016–2022)Kristina M. Ilieva · King's College London7 papers (2014–2019)Silvia Mele · University of London6 papers (2017–2020)Sophie Papa · The London College5 papers (2017–2021)Alastair D. MacKenzie Ross · St Thomas' Hospital5 papers (2016–2022)Ricarda M. Hoffmann · Institute of Cancer Research5 papers (2017–2021)Mano Nakamura · Guy's Hospital5 papers (2017–2021)Sophia Tsoka · King's College London5 papers (2018–2022)R. J. C. Harris · Adaptimmune (United Kingdom)4 papers (2019–2022)Isabel Corrêa · Centro Universitário Internacional4 papers (2013–2016)Isioma U. Egbuniwe · University of Nottingham4 papers (2014–2016)Jitesh Chauhan · King's College London4 papers (2021–2022)