Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include MicroRNA in disease regulation, RNA modifications and cancer, RNA Research and Splicing, and Cancer-related molecular mechanisms research.
Fragile X syndrome patient-derived neurons developing in the mouse brain show <i>FMR1</i> -dependent phenotypes
MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities
Human-mouse chimeric Fragile X syndrome model reveals FMR1-dependent neuronal phenotypes
Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions
Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate
Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification
The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth
The E–Id protein axis modulates the activities of the PI3K–AKT–mTORC1–Hif1a and c-myc/p19Arf pathways to suppress innate variant T <sub>FH</sub> cell development, thymocyte expansion, and lymphomagenesis
Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease
MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer
MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways