Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, RNA modifications and cancer, Epigenetics and DNA Methylation, and Hepatitis B Virus Studies.
Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression
Correction: Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/ GPX4 expression
PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1
SF3B4 Regulated Alternative Splicing that Produced an Oncogenic Isoform of HOXA11-AS to Promote Glycolytic Reprogramming and ESCC Progression
Cell-cycle-dependent phosphorylation of RRM1 ensures efficient DNA replication and regulates cancer vulnerability to ATR inhibition
γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A
Cellular energy stress induces AMPK-mediated regulation of glioblastoma cell proliferation by PIKE-A phosphorylation
Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth
Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin
Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling
Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling
Tyr Phosphorylation of PDP1 Toggles Recruitment between ACAT1 and SIRT3 to Regulate the Pyruvate Dehydrogenase Complex
Lysine Acetylation Activates 6-Phosphogluconate Dehydrogenase to Promote Tumor Growth
Tyr-301 Phosphorylation Inhibits Pyruvate Dehydrogenase by Blocking Substrate Binding and Promotes the Warburg Effect
Tyr-94 Phosphorylation Inhibits Pyruvate Dehydrogenase Phosphatase 1 and Promotes Tumor Growth
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation
micro<scp>RNA</scp>‐133a regulates the cell cycle and proliferation of breast cancer cells by targeting epidermal growth factor receptor through the <scp>EGFR</scp>/<scp>A</scp>kt signaling pathway
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth