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Shawn M. Lyons

Malaysia Genome Institute · US
Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include RNA Research and Splicing, RNA modifications and cancer, RNA and protein synthesis mechanisms, and Endoplasmic Reticulum Stress and Disease.
h-index
28
citations
4,783
works
76
NIH funding
primary concept
Biology
email

Recent publications

Stress granules are shock absorbers that prevent excessive innate immune responses to dsRNA
Molecular Cell 2023cited by 140position: middledoi
The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells
The American Journal of Human Genetics 2023cited by 9position: middledoi
Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases
Frontiers in Molecular Biosciences 2022cited by 31position: middledoi
Early rRNA processing is a stress-dependent regulatory event whose inhibition maintains nucleolar integrity
Nucleic Acids Research 2021cited by 78position: lastdoi
SDE2 is an essential gene required for ribosome biogenesis and the regulation of alternative splicing
Nucleic Acids Research 2021cited by 21position: middledoi
MVP Expression Facilitates Tumor Cell Proliferation and Migration Supporting the Metastasis of Colorectal Cancer Cells
International Journal of Molecular Sciences 2021cited by 16position: middledoi
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization
Cell 2020cited by 840position: middledoi
snoRNPs: Functions in Ribosome Biogenesis
Biomolecules 2020cited by 135position: lastdoi
Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2
Molecular Cell 2020cited by 131position: middledoi
eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function
Nucleic Acids Research 2020cited by 106position: firstdoi
Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus
Molecular Cell 2020cited by 68position: middledoi
Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation
Biomolecules 2020cited by 38position: middledoi
Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins?
Cancers 2020cited by 31position: middledoi
Stable tRNA halves can be sorted into extracellular vesicles and delivered to recipient cells in a concentration-dependent manner
RNA Biology 2019cited by 69position: middledoi
RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms
Journal of Molecular Biology 2017cited by 454position: middledoi
Stress-specific differences in assembly and composition of stress granules and related foci
Journal of Cell Science 2017cited by 302position: middledoi
G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits
The Journal of Cell Biology 2016cited by 679position: middledoi
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression
Nucleic Acids Research 2016cited by 254position: firstdoi
The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches
Cell Reports 2016cited by 195position: middledoi
Systematic reconstruction of RNA functional motifs with high-throughput microfluidics
Nature Methods 2012cited by 72position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Pavel Ivanov · Udmurt State University14 papers (2016–2023)Paul Anderson · Harvard University7 papers (2016–2022)Nancy Kedersha · Harvard University4 papers (2016–2020) · 3 papers (2017–2021)Sandeep Ojha · Motilal Nehru National Institute of Technology3 papers (2020–2021)Marta M. Fay · Huntsman Cancer Institute3 papers (2017–2022) · 2 papers (2021–2021)Sulochan Malla · National Institutes of Health2 papers (2020–2021) · 2 papers (2020–2020)Christopher A. Achorn · Rockefeller University2 papers (2016–2017) · 2 papers (2021–2021) · 2 papers (2021–2021) · 2 papers (2020–2022)Marco Mineo · The Ohio State University2 papers (2016–2020) · 2 papers (2020–2021) · 1 papers (2020–2020)Jillian G. Buchan · University of Washington1 papers (2020–2020)Rubén Ferrer-Luna · Brigham and Women's Hospital1 papers (2020–2020)Emily R. Mallick · Johns Hopkins Medicine1 papers (2019–2019)David W. Sanders · Southwestern Medical Center1 papers (2020–2020)