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Paola Picotti

ETH Zurich · CH
Area of research
Spectroscopy · Physiology
Research interest
Research interests include Advanced Proteomics Techniques and Applications, Alzheimer's disease research and treatments, Mass Spectrometry Techniques and Applications, and Parkinson's Disease Mechanisms and Treatments.
h-index
55
citations
15,848
works
200
NIH funding
primary concept
email

Recent publications

The main protease (Mpro) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII
Communications Biology 2025cited by 2position: middledoi
In situ analysis of osmolyte mechanisms of proteome thermal stabilization
Nature Chemical Biology 2024cited by 44position: lastdoi
On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
eLife 2024cited by 31position: middledoi
Structure of the connexin-43 gap junction channel in a putative closed state
eLife 2023cited by 32position: middledoi
Structure of the connexin-43 gap junction channel in a putative closed state
eLife 2023cited by 30position: middledoi
Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels
Science Advances 2023cited by 23position: middledoi
On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
eLife 2023cited by 16position: middledoi
Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly
Nature Cell Biology 2021cited by 61position: middledoi
Deciphering the signaling network of breast cancer improves drug sensitivity prediction
Cell Systems 2021cited by 41position: middledoi
Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis
Molecular Cell 2019cited by 58position: middledoi
Voices in methods development
Nature Methods 2019cited by 7position: middledoi
TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates
Nature Neuroscience 2018cited by 202position: middledoi
Phosphorylation of nuclear Tau is modulated by distinct cellular pathways
Scientific Reports 2018cited by 54position: middledoi
FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome
Proceedings of the National Academy of Sciences 2017cited by 58position: middledoi
Mitotic redistribution of the mitochondrial network by Miro and Cenp-F
Nature Communications 2015cited by 114position: middledoi
Relative Infestation Level and Sensitivity of Grapevine Cultivars to the Leafhopper<i>Empoasca vitis</i>(Hemiptera: Cicadellidae)
Journal of Economic Entomology 2015cited by 19position: middledoi
Global analysis of protein structural changes in complex proteomes
Nature Biotechnology 2014cited by 414position: lastdoi
RETRACTED: Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration <i>in vivo</i>
Brain 2014cited by 240position: middledoi
Modules, networks and systems medicine for understanding disease and aiding diagnosis
Genome Medicine 2014cited by 199position: middledoi
Calcineurin determines toxic versus beneficial responses to α-synuclein
Proceedings of the National Academy of Sciences 2014cited by 135position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 4 papers (2014–2017)Paul J. Boersema · Utrecht University3 papers (2014–2018) · 3 papers (2023–2023)Chao Qi · Kunming University of Science and Technology3 papers (2023–2023) · 3 papers (2023–2023) · 3 papers (2023–2023)Mario Bortolozzi · University of Padua3 papers (2023–2023)Erva Bayraktar · University of Padua3 papers (2023–2023)Roland Riek · ETH Zurich3 papers (2014–2024) · 2 papers (2023–2023) · 2 papers (2023–2023)Witek Kwiatkowski · ETH Zurich2 papers (2023–2024)Jason Greenwald · ETH Zurich2 papers (2023–2024)Susan Lindquist · Massachusetts Institute of Technology2 papers (2014–2017)David Rhyner · ETH Zurich2 papers (2023–2024) · 2 papers (2014–2015)Valeriya Baru · Q-State Biosciences (United States)2 papers (2014–2017)Francesco Luigi Gervasio · University of Geneva2 papers (2023–2023)Natalie de Souza · University of Zurich2 papers (2021–2024)Diego Lopez‐Pigozzi · University of Padua2 papers (2023–2023)