Jan R. Kraehling — Dartmouth College

Area of research

Physiology · Cardiology and Cardiovascular Medicine

Research interest

Research focused on Soluble guanylyl cyclase and Cyclic guanosine monophosphate, with related work in Kidney, Nitric oxide, Endocrinology. Notable publications include 'The Impact of the Nitric Oxide (NO)/Soluble Guanylyl Cyclase (sGC) Signaling Cascade on Kidney Health and Disease: A Preclinical Perspective', 'Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney', and 'Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic preclinical models of chronic kidney disease'.

Recent publications

Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney

British Journal of Pharmacology 2021cited by 45position: middledoi

Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic preclinical models of chronic kidney disease

Naunyn-Schmiedeberg s Archives of Pharmacology 2021cited by 31position: middledoi

The Novel Soluble Guanylyl Cyclase (sGC) Activator Runcaciguat Induced Renal Vasodilation and Reduced Kidney Damage in a Rat CKD Model

Journal of the American Society of Nephrology 2020cited by 1position: middledoi

The Impact of the Nitric Oxide (NO)/Soluble Guanylyl Cyclase (sGC) Signaling Cascade on Kidney Health and Disease: A Preclinical Perspective

International Journal of Molecular Sciences 2018cited by 98position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Frank Eitner · Ludwig-Maximilians-Universität München4 papers (2018–2021)— · 4 papers (2018–2021)Peter Sandner · Medizinische Hochschule Hannover4 papers (2018–2021)— · 3 papers (2020–2021)— · 3 papers (2020–2021)— · 2 papers (2020–2021)Frank Schweda · University of Regensburg2 papers (2020–2021)Andreas Patzak · Humboldt-Universität zu Berlin2 papers (2020–2021)Min Xu · University of Shanghai for Science and Technology1 papers (2021–2021)Shalini M Krishnan · University of Glasgow1 papers (2018–2018)— · 1 papers (2021–2021)— · 1 papers (2020–2020)— · 1 papers (2021–2021)Johannes‐Peter Stasch · Technical University of Munich1 papers (2021–2021)— · 1 papers (2021–2021)Ilka Mathar · KU Leuven1 papers (2021–2021)Susanne Feil · University of Tübingen1 papers (2021–2021)— · 1 papers (2020–2020)— · 1 papers (2021–2021)— · 1 papers (2020–2020)

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