Area of research
Cellular and Molecular Neuroscience · Molecular Biology
Research interest
Research focused on Neuroscience and Spinocerebellar ataxia, with related work in Neurodegeneration, Pathogenesis, Phenotype. Notable publications include 'Antisense oligonucleotide–mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles', 'Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles', and 'Spatial and Temporal Diversity of Astrocyte Phenotypes in Spinocerebellar Ataxia Type 1 Mice'.
Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease
Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles
Spatial and Temporal Diversity of Astrocyte Phenotypes in Spinocerebellar Ataxia Type 1 Mice
Antisense oligonucleotide–mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles