Area of research
Molecular Biology · Immunology and Allergy
Research interest
Research interests include PI3K/AKT/mTOR signaling in cancer, Cell Adhesion Molecules Research, Pancreatic and Hepatic Oncology Research, and Chronic Lymphocytic Leukemia Research.
Cardiovascular Toxicities of Immune Therapies for Cancer – A Scientific Statement of the Heart Failure Association (HFA) of the ESC and the ESC Council of Cardio-Oncology
An intrinsic mechanism of metabolic tuning promotes cardiac resilience to stress
Priorities in Cardio-Oncology Basic and Translational Science
Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases
Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease
Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function
Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart
Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance
The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary cilium
Mutations in PIK3C2A cause syndromic short stature, skeletal abnormalities, and cataracts associated with ciliary dysfunction
p110γ deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity
Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth
The Innate Immune System in Chronic Cardiomyopathy: A European Society of Cardiology (Esc) Scientific Statement from the Working Group on Myocardial Function of the ESC
Functions of PDE3 Isoforms in Cardiac Muscle
An Integrative Translational Approach to Study Heart Failure with Preserved Ejection Fraction: A Position Paper from the Working Group on Myocardial Function of the European Society of Cardiology
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression
Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits
Contractile Function During Angiotensin-II Activation
Targeting Myocardial Remodelling to Develop Novel Therapies for Heart Failure
Hemopexin Therapy Improves Cardiovascular Function by Preventing Heme-Induced Endothelial Toxicity in Mouse Models of Hemolytic Diseases
PI3-Kinase γ Promotes Rap1a-Mediated Activation of Myeloid Cell Integrin α4β1, Leading to Tumor Inflammation and Growth
Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction
NADPH Oxidases in Heart Failure: Poachers or Gamekeepers?
Phosphoinositide 3-Kinase γ Protects Against Catecholamine-Induced Ventricular Arrhythmia Through Protein Kinase A–Mediated Regulation of Distinct Phosphodiesterases
Anchoring Proteins as Regulators of Signaling Pathways
Ablation of Calcineurin Aβ Reveals Hyperlipidemia and Signaling Cross-talks with Phosphodiesterases