Area of research
Spectroscopy · Materials Chemistry
Research interest
Research focused on Hyperpolarization (physics) and Ligand (biochemistry), with related work in Fragment (logic), Polarization (electrochemistry), Spin diffusion. Notable publications include 'NMR-based analysis of protein–ligand interactions', 'Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities', and 'Direct observation of hyperpolarization breaking through the spin diffusion barrier'.
Zero- to Ultralow-Field Nuclear Magnetic Resonance Enhanced with Dissolution Dynamic Nuclear Polarization
Direct observation of hyperpolarization breaking through the spin diffusion barrier
Porous functionalized polymers enable generating and transporting hyperpolarized mixtures of metabolites
An automated system for fast transfer and injection of hyperpolarized solutions
Dipolar order mediated <sup>1</sup> H → <sup>13</sup> C cross-polarization for dissolution-dynamic nuclear polarization
1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery
Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor
Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities
Ligand-Orientation Based Fragment Selection in STD NMR Screening
Comparing Binding Modes of Analogous Fragments Using NMR in Fragment-Based Drug Design: Application to PRDX5
Protein–ligand structure guided by backbone and side-chain proton chemical shift perturbations
NMR-based analysis of protein–ligand interactions