Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, Cancer Immunotherapy and Biomarkers, Bioinformatics and Genomic Networks, and Glioma Diagnosis and Treatment.
Tumor DNA methylation subtypes predict immunotherapy outcomes in pleural mesothelioma patients in the NIBIT-EPI-MESO study
Restraint of cancer cell plasticity by spatial homotypic clustering
Activating antiviral immune responses potentiates immune checkpoint inhibition in glioblastoma models
MiR-423-5p is a metabolic and growth tuner in hepatocellular carcinoma via MALAT-1 and mitochondrial interaction
DNA methylation status classifies pleural mesothelioma cells according to their immune profile: implication for precision epigenetic therapy
Glioblastoma resistance to EGFR antibody-drug conjugate is driven by transcriptional reprogramming and TEK-induced EGFR suppression
A detailed guide to assessing genome assembly based on long-read sequencing data using Inspector
Knowledge-informed multimodal cfDNA analysis improves sensitivity and generalization in cancer detection
Big databases and biobanks for studying the links between CKD, cognitive impairment, and dementia
Abstract 4841: DNA methylation status classifies pleural mesothelioma cells according to their immune profile: implication for precision epigenetic therapy
Pan-cancer proteogenomics characterization of tumor immunity
Epigenetic remodeling to improve the efficacy of immunotherapy in human glioblastoma: pre-clinical evidence for development of new immunotherapy approaches
Differential methylation of circulating free DNA assessed through cfMeDiP as a new tool for breast cancer diagnosis and detection of BRCA1/2 mutation
Identification of therapeutic targets in osteoarthritis by combining heterogeneous transcriptional datasets, drug-induced expression profiles, and known drug-target interactions
Cognitive decline related to chronic kidney disease as an exclusion factor from kidney transplantation: results from an international survey
Mutational landscape of inflammatory breast cancer
Abstract LB241: FateAI: Analysis of circulating DNA fragmentomics with an artificial intelligence model for cancer screening
LBA47 Nivolumab plus ipilimumab and ASTX727 or nivolumab plus ipilimumab in PD-1 resistant metastatic melanoma: Primary analysis of the randomized phase II NIBIT-ML1 study
The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDH <sup>mut</sup> gliomas
KS02.5.A THE ONCOMETABOLITE D-2-HYDROXYGLUTARATE PROMOTES DNA HYPERMETHYLATION AT LINEAGE-SPECIFIC ENHANCERS CONTROLLING MICROGLIAL ACTIVATION IN IDH-MUTATED GLIOMAS
DNA methylation status classifies pleural mesothelioma cells according to their immune profile: implication for precision epigenetic therapy
An integrated tumor, immune and microbiome atlas of colon cancer
Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation
A variational algorithm to detect the clonal copy number substructure of tumors from scRNA-seq data
Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin
Pan-cancer proteogenomics connects oncogenic drivers to functional states
Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy
Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures
Guadecitabine plus ipilimumab in unresectable melanoma: five-year follow-up and integrated multi-omic analysis in the phase 1b NIBIT-M4 trial
Deep learning integrates histopathology and proteogenomics at a pan-cancer level