Area of research
Hematology · Oncology
Research interest
Research interests include Hematopoietic Stem Cell Transplantation, CAR-T cell therapy research, Virus-based gene therapy research, and Immune Cell Function and Interaction.
IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy
Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency
Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing
IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing
3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells
Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency
Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy
The Metabolic Landscape of Thymic T Cell Development In Vivo and In Vitro
Artificial thymic organoids represent a reliable tool to study T-cell differentiation in patients with severe T-cell lymphopenia
Nidogen‐1 Mitigates Ischemia and Promotes Tissue Survival and Regeneration
Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells
MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment
Stimulation of Hair Growth by Small Molecules that Activate Autophagy
Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer
Myeloid Disease Mutations of Splicing Factor SRSF2 Cause G2-M Arrest and Skewed Differentiation of Human Hematopoietic Stem and Progenitor Cells
Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids
The T-ALL related gene BCL11B regulates the initial stages of human T-cell differentiation
Medial HOXA genes demarcate haematopoietic stem cell fate during human development
Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages
Dynamics of HSPC Repopulation in Nonhuman Primates Revealed by a Decade-Long Clonal-Tracking Study
GPI-80 Defines Self-Renewal Ability in Hematopoietic Stem Cells during Human Development
Perivascular support of human hematopoietic stem/progenitor cells
Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy
Human Developmental Chondrogenesis as a Basis for Engineering Chondrocytes from Pluripotent Stem Cells
Gene therapy for adenosine deaminase–deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans
Lymphoid priming in human bone marrow begins before expression of CD10 with upregulation of L-selectin
Critical Differences in Hematopoiesis and Lymphoid Development between Humans and Mice