Area of research
Immunology · Genetics
Research interest
Research interests include Coagulation, Bradykinin, Polyphosphates, and Angioedema, T-cell and B-cell Immunology, Atherosclerosis and Cardiovascular Diseases, and Immune Cell Function and Interaction.
Sepsis‐induced <scp>NET</scp> formation requires <scp>MYD88</scp> but is independent of <scp>GSDMD</scp> and <scp>PAD4</scp>
Targeting NETs using dual-active DNase1 variants
The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
Repetitive Antigen Responses of LDL-Reactive CD4+ T Cells Induce Tr1 Cell–Mediated Immune Tolerance
In-vivo functions and regulation of polyphosphate in the vascular system
An Update on Safe Anticoagulation
Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood
Commentary on “Pharmacological profile of asundexian, a novel, orally bioavailable inhibitor of factor XIa”: Small molecule factor XIa inhibitor asundexian allows for safer anticoagulation
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia
Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation
Identification of the factor XII contact activation site enables sensitive coagulation diagnostics
An update on factor XII-driven vascular inflammation
Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate
Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation
Low-Density Lipoprotein-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice
Alternative Splicing of FOXP3—Virtue and Vice
Hypercholesterolemia Enhances T Cell Receptor Signaling and Increases the Regulatory T Cell Population
IL-1β promotes Th17 differentiation by inducing alternative splicing of FOXP3