Area of research
Genetics · Psychiatry and Mental health
Research interest
Research interests include Genetic Associations and Epidemiology, Genomics and Rare Diseases, Genomic variations and chromosomal abnormalities, and Genetics and Neurodevelopmental Disorders.
Multitrait analyses identify genetic variants associated with aortic valve function and aortic stenosis risk.
Impact of Preeclampsia Duration on Long-Term Cardiovascular Disease Risk.
Genetic regulation across germline and somatic variation on the Y chromosome contributes to type 2 diabetes
Fine-mapping a genome-wide meta-analysis of 98,374 migraine cases identifies 181 sets of candidate causal variants.
Cross-sectional assessment of telephone- and computer-administered instruments in detection of cognitive impairment.
Blood donor biobank pipeline to collect genome-based samples for research.
Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy.
Validity of telephone-administered word list learning measures for assessment of episodic memory in aging and Alzheimer's disease.
Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk
Deleterious coding variation associated with autism is shared across ancestries
Leveraging transdiagnostic genetic liability to psychiatric disorders to dissect clinical outcomes of anorexia nervosa.
Genomic analyses implicate hormonal and metabolic dysregulation in polycystic ovary syndrome
Genome-Wide Association Analysis of Tic Disorders Reveals 6 Independent Risk Loci and Highlights Tic-Associated Cell Types and Brain Circuitry
Genome-wide association study identifies a functional myostatin variant increasing lean mass in humans
Exome sequencing directly implicates 68 genes in inflammatory bowel disease
Translational genomics of osteoarthritis in 1,962,069 individuals
The impact of common and rare genetic variants on bradyarrhythmia development
Rare genetic variation in PTPRB is associated with central serous chorioretinopathy, varicose veins and glaucoma
Cross-sectional study of plasma phosphorylated tau 217 in persons without dementia.
Rare genetic variation in PTPRB is associated with central serous chorioretinopathy, varicose veins and glaucoma.
Psychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database.
Genetic Susceptibility to Acute Viral Bronchiolitis.
Genetic Loci Associated With Periodontitis: The FinnGen Study Based on National Health Registers.
Monoallelic TYROBP deletion is a novel risk factor for Alzheimer's disease.
One-year employment outcome prediction after traumatic brain injury: A CENTER-TBI study.
Low prevalence of CWH43 variants among Finnish and Norwegian idiopathic normal pressure hydrocephalus patients: a cohort-based observational study.
Assessing the potential causal effects of 1099 plasma metabolites on 2099 binary disease endpoints.
Large-scale genome-wide analyses with proteomics integration reveal novel loci and biological insights into frailty.
Cost-effective non-additive GWAS across 2329 diseases in 500,349 individuals